Caries, pulpitis, and apical periodontitis increase health care costs and attendant loss of
economic productivity. They ultimately result in premature tooth loss and therefore …

Root canal therapy has been the predominant approach in endodontic treatment, wherein
the entire pulp is cleaned out and replaced with a gutta‐percha filling. However, living pulp …

Dental pulp tissue is vulnerable to infection. Entire pulp amputation followed by pulp-space
disinfection and filling with an artificial rubber-like material is employed to treat the infection …

Recent advances in biomaterial science and tissue engineering technology have greatly
spurred the development of regenerative endodontics. This has led to a paradigm shift in …

Regenerative medicine is based on stem cells, signals, and scaffolds. Dental pulp tissue has
the potential to regenerate dentin in response to noxious stimuli, such as caries. The …

The standard treatment modality for teeth with irreversibly damaged dental pulp is root canal
therapy, which involves complete removal of the soft tissue and obturation with a synthetic …

Tissue engineering is the science of design and manufacture of new tissues to replace
impaired or damaged ones. The key ingredients for tissue engineering are stem cells, the …

Dental pulp is a highly specialized mesenchymal tissue that has a limited regeneration
capacity due to anatomical arrangement and post-mitotic nature of odontoblastic cells. Entire …

Preserving the natural dentition in its normal form and function is one of the major goals of
endodontic treatment. Re-establishing the lost vitality and development of root maturation in …

Millions of teeth are saved each year by root canal therapy. Although current treatment
modalities offer high levels of success for many conditions, an ideal form of therapy might …