[HTML][HTML] Treating COVID-19: targeting the host response, not the virus

DS Fedson - Life, 2023 - mdpi.com
In low-and middle-income countries (LMICs), inexpensive generic drugs like statins, ACE
inhibitors, and ARBs, especially if used in combination, might be the only practical way to …

Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs

G Byttebier, L Belmans, M Alexander… - Human vaccines & …, 2021 - Taylor & Francis
The COVID-19 pandemic has disrupted life throughout the world. Newly developed vaccines
promise relief to people who live in high-income countries, although vaccines and …

[HTML][HTML] Considerations for statin therapy in patients with COVID‐19

S Dashti‐Khavidaki, H Khalili - Pharmacotherapy, 2020 - ncbi.nlm.nih.gov
Conclusion Taken together, although there is an urgent need for finding safe and available
options for treatment of COVID‐19 and its related fatal ARDS, we must balance our …

[HTML][HTML] Statins as early therapy to mitigate COVID-19 (SARS-CoV-2)-associated ARDS and cytokine storm syndrome–time is of the essence

N Teoh, G Farrell - Journal of Clinical and Translational Research, 2020 - ncbi.nlm.nih.gov
While most coronavirus disease 2019 (COVID-19) infections run a benign course with
recovery, the inexorable rise in case fatalities in several countries is grim testimony to the …

[HTML][HTML] Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial

N Ghati, A Roy, S Bhatnagar, S Bhati, S Bhushan… - Trials, 2020 - Springer
Objectives To assess the impact of adding statin (atorvastatin) and/or aspirin on clinical
deterioration in patients infected with SARS-CoV-2 who require hospitalisation. The safety of …

[HTML][HTML] Therapeutic strategies for severe COVID-19: a position paper from the Italian Society of Infectious and Tropical Diseases (SIMIT)

C Mussini, M Falcone, S Nozza, C Sagnelli… - Clinical Microbiology …, 2021 - Elsevier
Scope Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has
become pandemic, reaching almost one million death worldwide. At present standard …

[HTML][HTML] Statin and aspirin as adjuvant therapy in hospitalised patients with SARS-CoV-2 infection: a randomised clinical trial (RESIST trial)

N Ghati, S Bhatnagar, M Mahendran, A Thakur… - BMC infectious …, 2022 - Springer
Background Statins and aspirin have been proposed for treatment of COVID-19 because of
their anti-inflammatory and anti-thrombotic properties. Several observational studies have …

[HTML][HTML] COVID-19 treatment guidelines: do they really reflect best medical practices to manage the pandemic?

F Jirjees, AK Saad, Z Al Hano, T Hatahet… - Infectious Disease …, 2021 - mdpi.com
SARS-CoV-2 (COVID-19) has been changing the world since December 2019. A
comprehensive search into many COVID-19 treatment guidelines was conducted and …

Effectiveness of Rosuvastatin plus Colchicine, Emtricitabine/Tenofovir and a combination of them in hospitalized patients with SARS COVID-19

HG Gaitán-Duarte, C Álvarez-Moreno… - medRxiv, 2021 - medrxiv.org
ABSTRACT BACKGROUND The effectiveness of rosuvastatin plus colchicine,
emtricitabine/tenofovir, and of their combined use in hospitalized patients with coronavirus …

[HTML][HTML] Evaluation of the current therapeutic approaches for COVID-19: a systematic review and a meta-analysis

Z Abdelrahman, Q Liu, S Jiang, M Li, Q Sun… - Frontiers in …, 2021 - frontiersin.org
Background: Limited data on the efficacy and safety of currently applied COVID-19
therapeutics and their impact on COVID-19 outcomes have raised additional concern …