Human neural tube defects: genetic causes and prevention
Neural tube defects (NTDs) are severe congenital malformations affecting 1–2 in 1,000 live
births, whose etiology is multifactorial, involving environmental and genetic factors. NTDs …
births, whose etiology is multifactorial, involving environmental and genetic factors. NTDs …
Investigations into the etiology of neural tube defects
RM Cabrera, DS Hill, AJ Etheredge… - Birth Defects Research …, 2004 - Wiley Online Library
Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …
births, yet the mechanisms by which they arise are unknown. There have been consistent …
Genetic basis of neural tube defects
AG Bassuk, Z Kibar - Seminars in pediatric neurology, 2009 - Elsevier
Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …
of the central nervous system. They result from failure of neural tube closure during early …
Genetic basis of susceptibility to environmentally induced neural tube defects
RH Finnell, J GELINEAU‐VAN WAES… - Annals of the new …, 2000 - Wiley Online Library
Neural tube defects (NTDs) are among the most common of all human congenital defects,
with multifactorial etiologies comprising both environmental and genetic components …
with multifactorial etiologies comprising both environmental and genetic components …
Genetics of neural tube defects
J Gelineau-van Waes, RH Finnell - Seminars in Pediatric Neurology, 2001 - Elsevier
Neural tube defects (NTDs) are common congenital malformations that occur when the
embryonic neural tube fails to close properly during early development. Although …
embryonic neural tube fails to close properly during early development. Although …
Neural tube defects
NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …
defects of the central nervous system that originate during embryonic development when the …
The role of folate transport and metabolism in neural tube defect risk
RC Barber, EJ Lammer, GM Shaw, KA Greer… - Molecular genetics and …, 1999 - Elsevier
Neural tube defects (NTDs) are common congenital malformations in humans. While
etiologically heterogeneous, for the most part they are multifactorial in their pathogenesis …
etiologically heterogeneous, for the most part they are multifactorial in their pathogenesis …
Folate and epigenetic mechanisms in neural tube development and defects
SV Meethal, KJ Hogan, CS Mayanil, BJ Iskandar - Child's nervous system, 2013 - Springer
Introduction Multiple genetic and epigenetic factors involved in central nervous system
(CNS) development influence the incidence of neural tube defects (NTDs). Discussion The …
(CNS) development influence the incidence of neural tube defects (NTDs). Discussion The …
Genetics of neural tube defects
JG Hall, F Solehdin - Mental retardation and developmental …, 1998 - Wiley Online Library
Neural tube defects are a complex, heterogeneous, and multifactorial group of disorders. In
humans it is estimated that 80% of neural tube defects are “multifactorial” and are influenced …
humans it is estimated that 80% of neural tube defects are “multifactorial” and are influenced …
Epidemiology of neural tube defects
LE Mitchell - American journal of medical genetics Part C …, 2005 - Wiley Online Library
The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …
anencephaly, and spina bifida, has a long history. The most significant finding from these …