Ischemic heart disease is the leading cause of death worldwide and is frequently comorbid
with chronic kidney disease. Physiological communication is known to occur between the …

More effective therapeutic strategies for the prevention and treatment of acute kidney injury
(AKI) are needed to improve the high morbidity and mortality associated with this frequently …

Ischemia-reperfusion injury is the leading cause of acute kidney injury in a variety of clinical
settings such as renal transplantation and hypovolemic and/or septic shock. Strategies to …

Background Although recent studies indicate that renal ischemic preconditioning (IPC)
protects the kidney from ischemia-reperfusion (I/R) injury, the precise protective mechanism …

Background—Outcomes after acute myocardial infarction in patients with chronic kidney
disease are extremely poor. Ischemic conditioning techniques are among the most powerful …

MAPK activities, including JNK, p38, and ERK, are markedly enhanced after ischemia in
vivoand chemical anoxia in vitro. The relative extent of JNK, p38, or ERK activation has been …

Following ischaemic insult, tissue damage is extended after reperfusion, known as an
ischaemia reperfusion injury. Ischaemic conditioning—the application of transient, non …

Ischemic preconditioning has been shown to ameliorate injury due to subsequent ischemia
in several organs. However, relatively little is known about preconditioning and the kidney …

Acute as well as delayed ischemic preconditioning (IPC) provides protection against cardiac
and neuronal ischemia reperfusion (IR) injury. This study determined whether delayed …

Renal ischemia/reperfusion (I/R) is an alternation of renal hemodynamics, which results in
diverse postischemic responses and eventually acute kidney injury. Although renal ischemic …