Cleft lip or palate (CL/P) is a common facial defect present in 1: 700 live births and results in
substantial burden to patients. There are more than 500 CL/P syndromes described, the …

Nonsyndromic cleft lip with or without an associated cleft palate (NSCLP) is one of the most
common birth defects affecting 135,000 babies worldwide each year. It causes severe facial …

Cleft lip and/or cleft palate (CL/P) collectively are well known as being amongst the most
common birth defects but we still have difficulty explaining why the majority of cases occur …

Cleft of the lip with or without cleft palate (CL/P) represents one of the commonest congenital
malformations in Western countries. Based on their association with specific malformative …

Orofacial clefts are common birth defects and can occur as isolated, nonsyndromic events or
as part of Mendelian syndromes. There is substantial phenotypic diversity in individuals with …

Clefts of the lip and/or palate (CL/P) are immediately recognizable disruptions of normal
facial structure. Approximately 1 in 700 children born have a cleft lip or a cleft palate or both …

Cleft lip and palate (CLP) are birth defects that affect the upper lip and the roof of the mouth.
CLP has a multifactorial etiology, comprising both genetic and environmental factors. In this …

This chapter summarizes current evidence regarding genetic etiologies for oral‐facial clefts,
both syndromic and nonsyndromic forms, particularly cleft lip with or without cleft palate …

Clefts of the lip and/or palate (CL/P) are among the most common birth defects worldwide.
The majority are non-syndromic where CL/P occurs in isolation of other phenotypes. Where …

Orofacial clefts include cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP), which
combined represent the largest group of craniofacial malformations in humans with an …