Background: The efficacy of combination empiric antibiotic therapy for all intensive care unit
(ICU) patients with community-acquired sepsis is a subject of ongoing debate in the era of …

Objectives Our primary goal was to evaluate the impact on in-hospital mortality rate of
adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort …

Objectives To determine the attributable mortality and excess length of stay (LOS)
associated with the use of inadequate empirical antimicrobial therapy in patients with sepsis …

Objective A sepsis protocol including institution-specific antibiotic recommendations based
on local susceptibility patterns was implemented at our institution. The purpose of this …

Background The appropriateness of antibiotics is the basis for improving the survival of
patients with sepsis. Objective This study aimed to determine the appropriateness of …

Aim: To evaluate epidemiology of sepsis in medical intensive care unit (ICU) in University
Hospital, and the impact of ICU performance and appropriate empirical antibiotic therapy on …

Objectives This study aimed to evaluate the appropriateness of antibiotic use and factors
associated with outcomes among sepsis patients in an intensive care unit (ICU). Methods …

Background: A retrospective study was conducted to investigate the validity and the
effectiveness of early empiric antibiotic and de-escalation therapy for the treatment of severe …

Background: The appropriate selection of empirical antibiotics based on the pattern of local
antibiotic resistance can reduce the mortality rate and increase the rational use of antibiotics …

Introduction: Sepsis is defined as a life-threatening organ dysfunction caused by a
dysregulated host response to an infection. Early recognition and administration of …