The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

Regenerating the human heart is a challenge that has engaged researchers and clinicians
around the globe for nearly a century. From the repair of the first septal defect in 1953 …

Cardiac regeneration is a rapidly evolving and controversial field of research. The
identification some 12 years ago of progenitor cells that reside within the heart spurred …

The global impetus to identify curative therapies has been fuelled by the unmet needs of
patients in the context of a growing heart failure pandemic. To date, regeneration trials in …

In the past decades, numerous preclinical studies and several clinical trials have evidenced
the feasibility of cell transplantation in treating heart diseases. Over the years, different …

Heart failure is the number one killer worldwide with~ 50% of patients dying within 5 years of
prognosis. The discovery of stem cells, which are capable of repairing the damaged portion …

From bone marrow transplants 5 decades ago to the most recent stem cell—derived organ
transplants, regenerative medicine is increasingly recognized as an emerging core …

Of the many diseases discussed in the context of stem cell therapy, those concerning the
heart account for almost one-third of the publications in the field. However, the long-term …

Cardiovascular disease is a leading cause of death worldwide, and thus there remains great
interest in regenerative approaches to treat heart failure. In the past 20 years, the field of …

Stem cell therapy for cardiac disease is an exciting but highly controversial research area.
Strategies such as cell transplantation and reprogramming have demonstrated both …