Rethinking causality and data complexity in brain lesion-behaviour inference and its implications for lesion-behaviour modelling

C Sperber - Cortex, 2020 - Elsevier
Modelling behavioural deficits based on structural lesion imaging is a popular approach to
map functions in the human brain, and efforts to translationally apply lesion-behaviour …

[PDF][PDF] Rethinking voxel-wise lesion-deficit analysis: a new challenge for computational neuropsychology

G Herbet, G Lafargue, H Duffau - Cortex, 2015 - academia.edu
This commentary refers to the recent study published in Brain entitled 'Human brain lesion-
deficit inference re-mapped', by Mah et al.(http://dx. doi. org/10.1093/brain/awu164). Over …

Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping

M Bowren Jr, J Bruss, K Manzel, D Edwards, C Liu… - Brain, 2022 - academic.oup.com
Clinicians and scientists alike have long sought to predict the course and severity of chronic
post-stroke cognitive and motor outcomes, as the ability to do so would inform treatment and …

Post‐stroke cognitive deficits rarely come alone: Handling co‐morbidity in lesion‐behaviour mapping

C Sperber, C Nolingberg, HO Karnath - 2020 - Wiley Online Library
Post‐stroke behavioural symptoms often correlate and systematically co‐occur with each
other, either because they share cognitive processes, or because their neural correlates are …

Dynamic causal modelling of brain–behaviour relationships

L Rigoux, J Daunizeau - NeuroImage, 2015 - Elsevier
In this work, we expose a mathematical treatment of brain–behaviour relationships, which
we coin behavioural Dynamic Causal Modelling or bDCM. This approach aims at …

High-dimensional therapeutic inference in the focally damaged human brain

T Xu, H Rolf Jäger, M Husain, G Rees, P Nachev - Brain, 2018 - academic.oup.com
Abstract See Thiebaut de Schotten and Foulon (doi: 10.1093/brain/awx332) for a scientific
commentary on this article. Though consistency across the population renders the …

Interpreting and validating complexity and causality in lesion-symptom prognoses

ML Seghier, CJ Price - Brain Communications, 2023 - academic.oup.com
This paper considers the steps needed to generate pragmatic and interpretable lesion-
symptom mappings that can be used for clinically reliable prognoses. The novel …

Lesion network mapping: where do we go from here?

AD Boes - Brain, 2021 - academic.oup.com
I read with great interest the recent article by Salvalaggio and colleagues in Brain,'Post-
stroke deficit prediction from lesion and indirect structural and functional disconnection' …

Power in voxel-based lesion-symptom mapping

DY Kimberg, HB Coslett, MF Schwartz - Journal of cognitive …, 2007 - direct.mit.edu
Lesion analysis in brain-injured populations complements what can be learned from
functional neuroimaging. Voxel-based approaches to mapping lesion-behavior correlations …

Mapping human brain lesions and their functional consequences

HO Karnath, C Sperber, C Rorden - Neuroimage, 2018 - Elsevier
Neuroscience has a long history of inferring brain function by examining the relationship
between brain injury and subsequent behavioral impairments. The primary advantage of this …