Biomarkers in pancreatic cancer as analytic targets for nanomediated imaging and therapy

CM Grapa, L Mocan, D Crisan, M Florea, T Mocan - Materials, 2021 - mdpi.com
As the increase in therapeutic and imaging technologies is swiftly improving survival
chances for cancer patients, pancreatic cancer (PC) still has a grim prognosis and a rising …

Current status of biomarker and targeted nanoparticle development: The precision oncology approach for pancreatic cancer therapy

L Zhu, C Staley, D Kooby, B El-Rays, H Mao, L Yang - Cancer letters, 2017 - Elsevier
Pancreatic cancer remains one of the major causes of cancer-related mortality. The majority
of pancreatic cancer patients are diagnosed at the advanced stage with unresectable and …

The New Era of Pancreatic Cancer Treatment: Application of Nanotechnology Breaking Through Bottlenecks

W Luo, T Zhang - Cancer Letters, 2024 - Elsevier
Since the advent of nanomedicine, physicians have harnessed these approaches for the
prophylaxis, detection, and therapy of life-threatening diseases, particularly cancer …

Nanomedicine for overcoming therapeutic and diagnostic challenges associated with pancreatic cancer

D Iyengar, K Tatiparti, NS Gavande, S Sau, AK Iyer - Drug Discovery Today, 2022 - Elsevier
Highlights•There are no reliable biomarkers for early detection of pancreatic cancer.•There
are limited screening methods for diagnosis of pancreatic cancer.•Nanoparticles can …

Emerging inorganic nanomaterials for pancreatic cancer diagnosis and treatment

F Yang, C Jin, S Subedi, CL Lee, Q Wang… - Cancer treatment …, 2012 - Elsevier
Pancreatic cancer is a devastating disease with incidence increasing at an alarming rate
and survival not improved substantially during the past three decades. Although enormous …

Overcoming the Limitations of Therapeutic Strategies to Combat Pancreatic Cancer using Nanotechnology

S Dhoundiyal, MA Alam - Current Cancer Drug Targets, 2023 - ingentaconnect.com
There is a significant unmet demand for the treatment of pancreatic cancer. Many patients do
not make it to past five years after diagnosis. The effectiveness of treatment varies greatly …

Nanomedicine for imaging and therapy of pancreatic adenocarcinoma

G Brachi, F Bussolino, G Ciardelli… - Frontiers in Bioengineering …, 2019 - frontiersin.org
Pancreatic adenocarcinoma has the worst outcome among all cancer types, with a 5-year
survival rate as low as 10%. The lethal nature of this cancer is a result of its silent onset …

Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer

J McCarroll, J Teo, C Boyer, D Goldstein… - Frontiers in …, 2014 - frontiersin.org
Despite improvements in our understanding of pancreatic cancer and the emerging concept
of personalized medicine for the treatment of this disease, it is still the fourth most common …

Recent advances in nanoparticle-mediated diagnosis and the treatment of pancreatic cancer

A Nedelcu, T Mocan, C Grapa, L Mocan - International Journal of …, 2021 - mdpi.com
Pancreatic cancer (PC), one of the most lethal solid tumors in humans, has a five-year
survival rate of only 4%. Surgical treatment is the only accepted therapy with curative intent …

Targeted Nanoparticle-Based Diagnostic and Treatment Options for Pancreatic Cancer

X Gu, T Minko - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) accounts for 90% of pancreatic
cancers. It is considered one of the deadliest cancers due to its high metastatic potential and …