In the present study, we examined the effects of CoCl 2 on multiple histone modifications at
the global level. We found that in both human lung carcinoma A549 cells and human …

The carcinogenic activity of crystalline NiS has been attributed to phagocytosis and
intracellular dissolution of the particles to yield Ni 2+ which is thought to enter the nucleus …

Nickel (Ni) is a widely distributed metal in the environment and an important pollutant due to
its widespread industrial applications. Ni has various toxicity in humans and experimental …

Exposure of intact Chinese hamster ovary cells to water-soluble NiCl2 and to particulate
crystalline NiS induced a concentration-dependent incidence of chromosomal aberrations …

The carcinogenicity of nickel compounds has been shown in numerous epidemiological and
animal studies. Carcinogenesis is generally considered as a multistep accumulation of …

Crystalline NiS particles are potent inducers of morphological transformation and are
actively phagocytosed by cells. Water-soluble nickel compounds are less potent, possibly …

It is well‐known that insoluble nickel compounds possess much more potent carcinogenic
activities as compared with soluble nickel compounds. Although it is assumed that the …

Nickel compounds are known to be carcinogenic to humans and animals. Cobalt
compounds produce tumors in animals and are probably carcinogenic to humans. The …

Background: Occupational exposure to nickel (Ni) is associated with an increased risk for
lung and nasal cancers. Ni compounds exhibit weak mutagenic activity, cause gene …

The C-terminal blocked tetrapeptides SHHK–and SAHK–, which represent the fragments
produced from the hydrolysis of the hexapeptides'–TASHHK–,–TESHHK–, and–TESAHK …