We use near-infrared dynamic multiple scattering of light [diffusing-wave spectroscopy
(DWS)] to detect the activation of the somato-motor cortex in 11 right-handed volunteers …

Optical approaches to investigate cerebral function and metabolism have long been applied
in invasive studies. From the neuron cultured in vitro to the exposed cortex in the human …

Optical methods have been used to measure physiological variables for decades, as is
apparent from other chapters in this book. However, the use of diffuse optical light for …

Diffuse optical imaging is a non-invasive technique for measuring changes in blood
oxygenation in the brain. This technique is based on the temporally and spatially resolved …

Near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS) are two
diffuse optical technologies for brain imaging that are sensitive to changes in hemoglobin …

Functional near-infrared spectroscopy (fNIRS) allows the ability to monitor brain activation
by measuring changes in the concentration of oxy-and deoxy-hemoglobin. Until now no …

Monitoring brain function with light in vivo has become a reality. The technology of detecting
and interpreting patterns of reflected light has reached a degree of maturity that now permits …

A time-resolved optical instrument allowing for noninvasive assessment of cerebral
oxygenation is presented. The instrument is equipped with picosecond diode lasers, fast …

The purpose of this study was to assess the accuracy of absolute cerebral blood flow (CBF)
measurements obtained by dynamic contrast-enhanced (DCE) near-infrared spectroscopy …

We review our most recent results on near-IR studies of human brain activity, which have
been evolving in two directions: detection of neuronal signals and measurements of …