Patients with ankylosing spondylitis (AS) have an increased risk of bone loss and vertebral
fractures. In this study, we explored the hypothesis that the excess bone loss and vertebral …

This study aimed to investigate the additional effect of ovariectomy-induced osteoporosis
(OP) on the pathology of knee osteoarthritis (OA) in a rat meniscectomized model …

Bone disease in rheumatoid arthritis affects the peri-articular and axial skeleton and is a
major cause of disability. Recent studies have shown that pro-inflammatory cytokines …

Introduction Femoral head avascular necrosis (AVN) is a recalcitrant disease of the hip that
leads to joint destruction. Osteoprotegerin (OPG), Receptor Activator of Nuclear Factor …

Intertrochanteric fractures occur most commonly in elderly patients. Osteoblasts and
osteoclasts have been reported to be regulated by the receptor activator of NF-κB ligand …

In the complex system of bone remodeling, the receptor activator of nuclear factor κB ligand
(RANKL)/osteoprotegerin (OPG) pathway is the coupling factor between bone formation and …

In experimental arthritis, blocking of the receptor activator of nuclear factor κB ligand
(RANKL) by osteo-protegerin (OPG) treatment prevents bone loss but not inflammation …

Objective. To determine whether serum markers of bone formation and resorption, used
individually or in combination, can be used to identify subgroups who lose cartilage volume …

Objective Dickkopf-1 (DKK-1) is an inhibitor of osteoblastogenesis, and its lower levels are
linked to new bone formation. The aim of this study was therefore to explore serum levels of …

The skeletal complications of rheumatoid arthritis (RA) include focal bone erosions and
juxtaarticular osteopenia at sites of active inflammation, as well as systemic osteopenia …