Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach
Background High throughput sequencing-by-synthesis is an emerging technology that
allows the rapid production of millions of bases of data. Although the sequence reads are …
allows the rapid production of millions of bases of data. Although the sequence reads are …
Determination of tag density required for digital transcriptome analysis: application to an androgen-sensitive prostate cancer model
H Li, MT Lovci, YS Kwon… - Proceedings of the …, 2008 - National Acad Sciences
High-throughput sequencing has rapidly gained popularity for transcriptome analysis in
mammalian cells because of its ability to generate digital and quantitative information on …
mammalian cells because of its ability to generate digital and quantitative information on …
Prostate cancer expression profiling by cDNA sequencing analysis
GM Huang, W Ng, J Farkas, L He, HA Liang, D Gordon… - Genomics, 1999 - Elsevier
Prostate cancer is a frequently diagnosed solid tumor that is originated mostly from prostate
epithelium. One of the key issues in prostate cancer research is to develop molecular …
epithelium. One of the key issues in prostate cancer research is to develop molecular …
Unique patterns of molecular profiling between human prostate cancer LNCaP and PC‐3 cells
MG Dozmorov, RE Hurst, DJ Culkin, BP Kropp… - The …, 2009 - Wiley Online Library
BACKGROUND Human prostate cancer LNCaP and PC‐3 cell lines have been extensively
used to study prostate cancer progression and to develop therapeutic agents. Although …
used to study prostate cancer progression and to develop therapeutic agents. Although …
IVT-seq reveals extreme bias in RNA sequencing
NF Lahens, IH Kavakli, R Zhang, K Hayer, MB Black… - Genome biology, 2014 - Springer
Background RNA-seq is a powerful technique for identifying and quantifying transcription
and splicing events, both known and novel. However, given its recent development and the …
and splicing events, both known and novel. However, given its recent development and the …
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression
JR Prensner, MK Iyer, OA Balbin… - Nature …, 2011 - nature.com
Noncoding RNAs (ncRNAs) are emerging as key molecules in human cancer, with the
potential to serve as novel markers of disease and to reveal uncharacterized aspects of …
potential to serve as novel markers of disease and to reveal uncharacterized aspects of …
Application of Affymetrix array and Massively Parallel Signature Sequencing for identification of genes involved in prostate cancer progression
AJ Oudes, JC Roach, LS Walashek, LJ Eichner… - BMC cancer, 2005 - Springer
Abstract Background Affymetrix GeneChip Array and Massively Parallel Signature
Sequencing (MPSS) are two high throughput methodologies used to profile transcriptomes …
Sequencing (MPSS) are two high throughput methodologies used to profile transcriptomes …
Alternative expression analysis by RNA sequencing
M Griffith, OL Griffith, J Mwenifumbo, R Goya… - Nature …, 2010 - nature.com
In alternative expression analysis by sequencing (ALEXA-seq), we developed a method to
analyze massively parallel RNA sequence data to catalog transcripts and assess differential …
analyze massively parallel RNA sequence data to catalog transcripts and assess differential …
Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing
Sequence-based methods for transcriptome characterization have typically relied on
generation of either serial analysis of gene expression tags or expressed sequence tags …
generation of either serial analysis of gene expression tags or expressed sequence tags …
Defining transcribed regions using RNA-seq
Next-generation sequencing technologies are revolutionizing genomics research. It is now
possible to generate gigabase pairs of DNA sequence within a week without time …
possible to generate gigabase pairs of DNA sequence within a week without time …
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