Background The survival rate among patients with intermediate-risk neuroblastoma who
receive dose-intensive chemotherapy is excellent, but the survival rate among patients who …

PURPOSE The primary objective of the Children's Oncology Group study ANBL0531
(ClinicalTrials. gov identifier: NCT00499616) was to reduce therapy for subsets of patients …

Purpose The goal of Pediatric Oncology Group 9243 was to improve outcomes for children
with intermediate-risk neuroblastoma (NB). Patients and Methods Patients were assigned to …

Neuroblastoma is the most common extra-cranial solid tumor of childhood and the most
common in the first year of life. It is a unique malignancy in that infants often present with …

Background The prognosis of high‐risk neuroblastoma patients has improved over the last
decades. However, many patients experience relapse after successful initial treatment. We …

Purpose The primary objective of Children's Oncology Group study P9641 was to
demonstrate that surgery alone would achieve 3-year overall survival (OS)≥ 95% for …

Background: Childhood neuroblastoma describes a heterogeneous group of extracranial
solid tumors, that are treated per risk profile. We sought to describe treatment patterns and …

PURPOSE Induction therapy is a critical component of the therapy of high-risk
neuroblastoma. We aimed to assess if the Memorial Sloan Kettering Cancer Center …

PURPOSE: A prospective Children's Cancer Group study, CCG-3881, has been completed
to determine if a more accurate prediction of prognosis by biologic features can identify …

Close international collaboration between pediatric oncologists has led to marked
improvements in the cure of patients, seen as a long-term overall survival rate of about 80 …