On tissue engineering field the research about skin substitutes represents historically the
most promising approach to heal acute and chronic skin wounds, reducing requirements for …

Extensive skin loss from a variety of conditions is associated with significant functional
morbidity and loss of life. In many patients, a limited number of donor sites available for …

Tissue-engineered skin equivalents composed of epidermal and dermal components have
been widely investigated for coverage of full-thickness skin defects. We developed a tissue …

The major applications of tissue-engineered skin substitutes are in promoting the healing of
acute and chronic wounds. Several approaches have been taken by commercial companies …

Skin substitutes composed of cultured cells and biopolymers provide alternative materials
for study of skin biology and pathology, treatment of skin wounds, safety testing of consumer …

Ideally tissue-engineered products should maintain the characteristics of the original tissue.
For example, skin represents orthokeratinized epithelium and oral gingiva represents …

Revolutionary advances in tissue engineering are redefining approaches to tissue repair
and transplantation through the creation of replacement tissues that remain biointeractive …

The soft tissue reconstruction of significant avulsed and/or surgically created tissue defects
requires the ability to manufacture substantial soft tissue constructs for repair of the resulting …

Soft tissue defects resulting from trauma, vascular disease, burns, and postoncologic
resections require reconstructive surgery for appropriate wound coverage and support …

Skin, the largest organ in the body, protects against toxins and microorganisms in the
environment and serves to prevent dehydration of all non-aquatic animals. Immune …