Endothelial progenitor cell transplantation decreases lymphangiogenesis and adverse myocardial remodeling in a mouse model of acute myocardial infarction

JH Park, JY Yoon, SM Ko, SA Jin, JH Kim… - … & molecular medicine, 2011 - nature.com
Cardiac lymphatic system in the remodeling after acute myocardial infarction (AMI) has been
overlooked. We wanted to investigate the role of bone marrow-derived endothelial …

[HTML][HTML] Lymphangiogenesis contributes to exercise-induced physiological cardiac growth

Y Bei, Z Huang, X Feng, L Li, M Wei, Y Zhu… - Journal of Sport and …, 2022 - Elsevier
Background Promoting cardiac lymphangiogenesis exerts beneficial effects for the heart.
Exercise can induce physiological cardiac growth with cardiomyocyte hypertrophy and …

The ebb and flow of cardiac lymphatics: a tidal wave of new discoveries

NR Harris, L Bálint, DM Dy, NR Nielsen… - Physiological …, 2023 - journals.physiology.org
The heart is imbued with a vast lymphatic network that is responsible for fluid homeostasis
and immune cell trafficking. Disturbances in the forces that regulate microvascular fluid …

Role of the lymphatic vasculature in cardiovascular medicine

N Telinius, VE Hjortdal - Heart, 2019 - heart.bmj.com
The lymphatic vasculature has traditionally been considered important for removal of
excessive fluid from the interstitial space, absorption of fat from the intestine and the immune …

Cardiac lymphatics–a new avenue for therapeutics?

T Vuorio, A Tirronen, S Ylä-Herttuala - Trends in Endocrinology & …, 2017 - cell.com
Recent progress in lymphatic vessel biology and in novel imaging techniques has
established the importance of the lymphatic vasculature as part of the cardiovascular …

The lymphatic system in zebrafish heart development, regeneration and disease modeling

X Feng, S Travisano, CA Pearson, CL Lien… - Journal of …, 2021 - mdpi.com
Heart disease remains the single largest cause of death in developed countries, and novel
therapeutic interventions are desperately needed to alleviate this growing burden. The …

Cardiac lymphatics are heterogeneous in origin and respond to injury

L Klotz, S Norman, JM Vieira, M Masters, M Rohling… - Nature, 2015 - nature.com
The lymphatic vasculature is a blind-ended network crucial for tissue-fluid homeostasis,
immune surveillance and lipid absorption from the gut. Recent evidence has proposed an …

M2b macrophages stimulate lymphangiogenesis to reduce myocardial fibrosis after myocardial ischaemia/reperfusion injury

C Wang, Y Yue, S Huang, K Wang, X Yang… - Pharmaceutical …, 2022 - Taylor & Francis
Context Therapeutic lymphangiogenesis is a new treatment for cardiovascular diseases. Our
previous study showed M2b macrophages can alleviate myocardial ischaemia/reperfusion …

Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration

MRM Harrison, X Feng, G Mo, A Aguayo, J Villafuerte… - Elife, 2019 - elifesciences.org
The cardiac lymphatic vascular system and its potentially critical functions in heart patients
have been largely underappreciated, in part due to a lack of experimentally accessible …

Lymphatic system identification, pathophysiology and therapy in the cardiovascular diseases

D Hu, L Li, S Li, M Wu, N Ge, Y Cui, Z Lian… - Journal of molecular and …, 2019 - Elsevier
The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the closed, high-pressure and circular blood vascular …