Analysis of IL-2, IL-4 and their receptors in clonally-related cell lines derived from a patient with a progressive cutaneous T-cell lymphoproliferative disorder

MA Wasik, DC Seldin, JR Butmarc, R Gertz… - Leukemia & …, 1996 - Taylor & Francis
Three clonally related T-cell lymphoma lines (PB-1, 2A, and 2B) were examined for
expression of IL-2, IL-4, and their receptors. All three lines were derived from a single patient …

Expression of IL-4 receptor on human T and B lymphocytes

H Zola, L Flego, H Weedon - Cellular immunology, 1993 - Elsevier
The expression of the interleukin-4 receptor on human blood and tonsil lymphocytes has
been studied using a monoclonal antibody and high-sensitivity immunofluorescence flow …

Establishment of an IL‐2 independent, human T‐cell line possessing only the p70 IL‐2 receptor

G Starkebaum, TP Loughran JR… - … journal of cancer, 1991 - Wiley Online Library
A continuous cell line was established from the blood of a patient (HH) with an aggressive
cutaneous T‐cell leukemia/lymphoma who lacked antibodies to human T lymphotrophic …

Differential expression of interleukin‐2 receptors (α and β chain) in mature lymphoid neoplasms

K Nakase, K Kita, K Nasu, T Ueda… - American journal of …, 1994 - Wiley Online Library
We investigated the expression of interleukin‐2 receptors (IL‐2R) in 60 adult patients with
mature lymphoid neoplasms by flow cytometric analysis, using two monoclonal antibodies …

A majority of proliferating T cells in cutaneous malignant T cell lymphomas may lack the high affinity IL-2 receptor (CD25)

WH Boehncke, J Gerdes, M Wiese, K Kaltoft… - Archives of …, 1993 - Springer
IL-2 is a major growth factor for all T-cell subsets acting via a specific membrane receptor. To
investigate its role in the pathogenesis of cutaneous T-cell lymphomas (CTCLs), we …

Cytoplasmic interleukin-4 (IL-4) and surface IL-4 receptor expression in patients with B-cell lymphocytic leukemia

A Kaminski, A Demaine… - Blood, The Journal of the …, 1998 - ashpublications.org
In particular, interleukin-4 (IL-4) prevents B-CLL cell clones from entering spontaneous
apoptosis by increasing the expression of bcl-25 and protects B-CLL cells against anti-APO1 …

Interleukin-7 receptor expression in cutaneous T-cell lymphomas.

M Bagot, D Charlue, ML Boulland… - British Journal of …, 1996 - search.ebscohost.com
Abstract Keratinocyte-derived interleukin-7 (IL-7) is a potent growth factor for some
cutaneous T-cell lymphomas (CTCL). We investigated the expression of IL-7 receptor (IL …

Interleukin-7 is a growth factor for Sézary lymphoma cells.

A Dalloul, L Laroche, M Bagot… - The Journal of …, 1992 - Am Soc Clin Investig
Sézary syndrome is a cutaneous T cell lymphoma characterized by infiltration of the skin by
CD4+ cells. These cells generally respond poorly to mitogens and T cell activators. We have …

Characterization and regulation of interleukin‐4 receptor in adult T‐cell leukemia cells

N Mori, F Shirakawa, S Murakami… - European journal of …, 1996 - Wiley Online Library
We studied the expression of the receptor of interleukin (IL)‐4, one of the T cell growth
factors, on fresh peripheral blood leukemic cells from adult T‐cell leukemia (ATL) patients …

Functional and molecular characterization of B cell line derived interleukin-1 alpha.

FA Vyth-Dreese, A Hekman, J Wijffels, M Geertsma… - Leukemia, 1989 - europepmc.org
The cytokine secreted by a human hybrid B cell line (STS 25) obtained by fusion of the B
lymphoblastoid cell line WI-L2-729-HF2 with neoplastic B cells from a patient with B cell non …