[HTML][HTML] Safety, tolerability and efficacy of eslicarbazepine acetate as adjunctive therapy in patients aged≥ 65 years with focal seizures

R Costa, B Steinhoff, H Gama, F Ikedo, JF Rocha… - Drugs & Aging, 2018 - Springer
Background The incidence of epilepsy is high within the first few years of life, stabilizes over
the second through fifth decades, and then rises again. Treatment of elderly patients with …

[HTML][HTML] Effectiveness and safety/tolerability of eslicarbazepine acetate in epilepsy patients aged≥ 60 versus< 60 years: a subanalysis from the Euro-Esli Study

C Lawthom, P Bermejo, D Campos, R McMurray… - Neurology and …, 2019 - Springer
Introduction Clinical practice studies help guide antiepileptic drug (AED) therapy in patient
groups routinely excluded from clinical trials, such as the elderly. The Euro-Esli study …

[HTML][HTML] Efficacy and safety of eslicarbazepine-acetate in elderly patients with focal epilepsy: case series

A Gómez-Ibáñez, JM Serratosa, E Guillamón, M Garcés… - Seizure, 2017 - Elsevier
Purpose Eslicarbazepine-acetate (ESL) is a third generation antiepileptic drug licensed as
adjunctive therapy in adults with focal seizures. Efficacy and safety of ESL have been …

[HTML][HTML] Comparative analysis of the safety and tolerability of eslicarbazepine acetate in older (≥ 60 years) and younger (18–59 years) adults

E Andermann, W Rosenfeld, P Penovich, J Rogin… - Epilepsy Research, 2021 - Elsevier
Objective To investigate the safety and tolerability of eslicarbazepine acetate (ESL), a once-
daily oral anti-seizure drug (ASD), in older and younger adult patient populations. Methods …

[HTML][HTML] Safety of eslicarbazepine acetate in elderly versus non-elderly patients with focal seizures: from pooled data of clinical studies to 8 years of post-marketing …

LM Magalhães, R Costa, M Vieira, J Moreira, H Gama… - Drug Safety, 2021 - Springer
Introduction The prevalence of epilepsy increases in elderly patients aged> 65 years, and
treatment is challenging because clinical data are limited. Objective Our objective was to …

Clinical outcomes of eslicarbazepine acetate monotherapy for focal‐onset seizures: A multicenter audit

BG Giráldez, I Garamendi‐Ruiz, J Zurita… - Acta Neurologica …, 2019 - Wiley Online Library
Objective To assess the effectiveness and tolerability of eslicarbazepine acetate (ESL)
monotherapy in routine clinical practice for the treatment of focal‐onset seizures. Methods …

[HTML][HTML] Clinical experience with eslicarbazepine acetate in adults with sub-analysis of elderly

MK Nielsen, V Petrenaite, NB Andersen - Seizure, 2017 - Elsevier
Purpose Eslicarbazepine acetate (ESL) is indicated for treatment of focal epilepsy. Our aim
was to evaluate the effect and tolerability of ESL in elderly and younger adults. The primary …

[HTML][HTML] Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: a historical-control phase III …

MP Jacobson, L Pazdera, P Bhatia, T Grinnell… - BMC neurology, 2015 - Springer
Abstract Background Eslicarbazepine acetate (ESL, Aptiom®) is a once-daily (QD)
anticonvulsant, approved as adjunctive treatment of partial-onset seizures (POS). It is …

[HTML][HTML] Euro-Esli: a European audit of real-world use of eslicarbazepine acetate as a treatment for partial-onset seizures

V Villanueva, M Holtkamp, N Delanty… - Journal of …, 2017 - Springer
Abstract The Euro-Esli study was an exploratory pooled analysis of data from 14 European
clinical practice studies, which was conducted to audit the real-world effectiveness, safety …

[HTML][HTML] Efficacy and safety of eslicarbazepine acetate as a first or later adjunctive therapy in patients with focal seizures

J Hixson, B Gidal, A Pikalov, Y Zhang, D Mehta… - Epilepsy Research, 2021 - Elsevier
Introduction We report outcomes from an open-label, non-randomized, 24-week study of
eslicarbazepine acetate (ESL) in adults at earlier and later stages of their treatment history …