Taste bud homeostasis in health, disease, and aging

P Feng, L Huang, H Wang - Chemical senses, 2014 - academic.oup.com
The mammalian taste bud is an onion-shaped epithelial structure with 50–100 tightly packed
cells, including taste receptor cells, supporting cells, and basal cells. Taste receptor cells …

Taste transduction and channel synapses in taste buds

A Taruno, K Nomura, T Kusakizako, Z Ma… - … -European Journal of …, 2021 - Springer
The variety of taste sensations, including sweet, umami, bitter, sour, and salty, arises from
diverse taste cells, each of which expresses specific taste sensor molecules and associated …

Distribution of gustatory sensitivities in rat taste cells: whole-cell responses to apical chemical stimulation

TA Gilbertson, JD Boughter, H Zhang… - Journal of …, 2001 - Soc Neuroscience
Several taste transduction mechanisms have been demonstrated in mammals, but little is
known about their distribution within and across receptor cells. We recorded whole-cell …

Signal transduction and information processing in mammalian taste buds

SD Roper - Pflügers Archiv-European Journal of Physiology, 2007 - Springer
The molecular machinery for chemosensory transduction in taste buds has received
considerable attention within the last decade. Consequently, we now know a great deal …

Taste reception

B Lindemann - Physiological reviews, 1996 - journals.physiology.org
Recent research on cellular mechanisms of peripheral taste has defined transduction
pathways involving membrane receptors, G proteins, second messengers, and ion …

Mammalian taste perception

PAS Breslin, AC Spector - Current Biology, 2008 - cell.com
The sense of taste is activated when certain classes of chemicals contact specialized
epithelial taste receptor cells in the tongue, palate, throat and, in some species, near the …

Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25

TR Clapp, KF Medler, S Damak, RF Margolskee… - BMC biology, 2006 - Springer
Background Taste receptor cells are responsible for transducing chemical stimuli from the
environment and relaying information to the nervous system. Bitter, sweet and umami stimuli …

[HTML][HTML] Common sense about taste: from mammals to insects

DA Yarmolinsky, CS Zuker, NJP Ryba - Cell, 2009 - cell.com
The sense of taste is a specialized chemosensory system dedicated to the evaluation of food
and drink. Despite the fact that vertebrates and insects have independently evolved distinct …

Discrimination of taste qualities among mouse fungiform taste bud cells

R Yoshida, A Miyauchi, T Yasuo… - The Journal of …, 2009 - Wiley Online Library
Multiple lines of evidence from molecular studies indicate that individual taste qualities are
encoded by distinct taste receptor cells. In contrast, many physiological studies have found …

[HTML][HTML] Taste isn't just for taste buds anymore

TE Finger, SC Kinnamon - F1000 biology reports, 2011 - ncbi.nlm.nih.gov
Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste
buds) and at least two distinct families of G protein-coupled receptor molecules that detect …