RATIONALE AND OBJECTIVES.: The authors performed this study to determine how
scanner temporal resolution affects image quality in high-resolution computed tomography …

Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests,
noninvasive imaging techniques provide complementary and valuable information that …

Many lung disease processes are characterized by structural and functional heterogeneity
that is not directly appreciable with traditional physiological measurements. Experimental …

Small animal models of lung fibrosis are essential for unraveling the molecular mechanisms
underlying human fibrotic lung diseases; additionally, they are useful for preclinical testing of …

Pulmonary functional imaging modalities such as computed tomography, magnetic
resonance imaging and nuclear imaging can quantitatively assess regional lung functional …

Lung function has been evaluated in both health and disease states by techniques, such as
pulmonary function tests, which generally study aggregate function. These decades old …

Chronic lung disease is a major worldwide health concern but better tools are required to
understand the underlying pathologies. Ventilation/perfusion (V/Q) single photon emission …

Research involved in modeling human lung disease conditions has provided insight into
disease development, progression, and treatment. In particular, mouse models of human …

Have you ever noticed the impact of images? As you pick up a textbook, read a paper, or
review a grant, have you noticed how your eye and mind quickly grasp and capture pictures …

Purpose: We seek to generate an atlas of the normal murine lung based on micro-CT
imaging. In-vivo imaging allows visualization of parenchymal density and small airways …