Imaging dynamic cellular events in the lung
MI Kotlikoff, NY Tallini - The Journal of general physiology, 2005 - rupress.org
Early in the last century, JS Haldane observed,“It is probable indeed that in some way or
other the air supply is proportioned to the blood supply, whether by regulation through the …
other the air supply is proportioned to the blood supply, whether by regulation through the …
The use of small animal imaging in respiratory disease drug discovery
The expansion of scientific knowledge and technology over the past decades did not result
in an increased rate of drug discoveries for respiratory diseases. Despite the identification of …
in an increased rate of drug discoveries for respiratory diseases. Despite the identification of …
Novel imaging-derived morphological and functional biomarkers of lung disease in mouse models
K Dekoster - 2022 - lirias.kuleuven.be
Pulmonary fibrosis is the replacement of healthy tissue by an excessive deposition of
extracellular matrix components leading to an irreversible destruction of the lung …
extracellular matrix components leading to an irreversible destruction of the lung …
Multimodal optical imaging
C Lawler, WA Suk, BR Pitt… - American Journal of …, 2003 - journals.physiology.org
The recent resurgence of interest in the use of intravital microscopy in lung research is a
manifestation of extraordinary progress in visual imaging and optical microscopy. This …
manifestation of extraordinary progress in visual imaging and optical microscopy. This …
A view on imaging in drug research and development for respiratory diseases
CJA van Echteld, N Beckmann - Journal of Pharmacology and Experimental …, 2011 - ASPET
With the incidence of respiratory diseases increasing throughout the world, new therapies
are needed. This review provides a short overview of different imaging techniques of interest …
are needed. This review provides a short overview of different imaging techniques of interest …
Longitudinal micro-CT provides biomarkers of lung disease and therapy in preclinical models, thereby revealing compensatory changes in lung volume
GV Velde, J Poelmans, E De Langhe… - Dis. Model …, 2016 - journals.biologists.com
Obstructive, interstitial, infectious and malignant lung diseases remain among the most
important health challenges and novel or improved therapeutic strategies are essential for …
important health challenges and novel or improved therapeutic strategies are essential for …
[图书][B] Functional imaging of the chest
HU Kauczor - 2004 - books.google.com
For a long time, imaging of the chest was based on the use of either radiography,
demonstrating lung morphology, or scintigraphy, looking at lung function. However, as a …
demonstrating lung morphology, or scintigraphy, looking at lung function. However, as a …
Delineation of an acquisition window within the respiratory cycle of laboratory animals
SP Holmes, M Thornton, P Gareau… - … Resolution Imaging in …, 1999 - cds.ismrm.org
Interest from pharmaceutical and genomic industries is expanding the field of laboratory
animals imaging because responses to novel drugs and phenotypic aberrations in …
animals imaging because responses to novel drugs and phenotypic aberrations in …
Functional airway imaging methods
JG Goldin - CT of the Airways, 2008 - Springer
The techniques for CT evaluation of the airway are directed at improving both the detection
and measurement of structural changes as well as providing quantitative measures of …
and measurement of structural changes as well as providing quantitative measures of …
Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …