Imaging in small animal models of lung disease is challenging, as existing technologies are
limited either by resolution or by the terminal nature of the imaging approach. Here, we …

The ability to view airways response directly during an asthmatic attack would clearly be of
great advantage in our understanding and treatment of airway hyperresponsiveness …

Small animal imaging is experiencing rapid development due to its importance in providing
high-throughput phenotypic data for functional genomics studies. We have developed a …

X-ray computed tomography is a reliable technique for the detection and longitudinal
monitoring of pulmonary nodules. In preclinical stages of diagnostic or therapeutic …

Dual modality micro-CT and SPECT imaging can play an important role in preclinical studies
designed to investigate mechanisms, progression, and therapies for acute lung injury in rats …

The advent of micro-computed tomography (microCT) has provided significant advancement
in our ability to generate clinically relevant assessments of lung health and disease in small …

Understanding how the mammalian respiratory system works and how it changes in disease
states and under the influence of drugs is frequently pursued in model systems such as …

Since the previous review on this topic of functional computed tomography (CT) and MRI of
the lung, significant advances have been made into the development of imaging based …

Measurements of lung function, including spirometry and body plethesmography, are easy
to perform and are the current clinical standard for assessing disease severity. However …

Real-time imaging of the intact lung allows for the visualization and analysis of pulmonary
vascular responses at a unique spatial and temporal resolution. For visual access to the …