The combination of high-resolution computed tomography (HRCT), rapid volumetric
scanning, and advanced image display and analysis applications software is a powerful …

Before microcomputed tomography (micro-CT) can be exploited to its full potential for
longitudinal monitoring of transgenic and experimental mouse models of lung diseases …

Mouse models are important for pulmonary research to gain insight into structure and
function in normal and diseased states, thereby extending knowledge of human disease …

Imaging-based assessments of lung function have evolved to provide a better
understanding of normal lung and the pathophysiology of lung disease. These …

More than 50 years ago, John West and colleagues (1) published their landmark study on
the vertical distribution of blood flow in the lung as a result of the interplay between the local …

Medical imaging has been increasingly used in respiratory research due to the rapid and
ongoing development of medical technology. Current imaging is almost entirely 3 …

Computed tomography (CT) has made remarkable advances in the depiction of morphologic
changes in the lungs. High-resolution CT has impacted profoundly on the detection …

The intention of this review is to provide a succinct overview about the availability and
relevance of major mouse models for lung cancer, commonly used imaging modalities and …

Regional changes in lung microstructure are an important component of several common
lung disorders and even in healthy lungs alveolar mechanics are poorly understood …