Immune microenvironment and response in prostate cancer using large population cohorts

X Ren, X Chen, X Zhang, S Jiang, T Zhang… - Frontiers in …, 2021 - frontiersin.org
Immune microenvironment of prostate cancer (PCa) is implicated in disease progression.
However, previous studies have not fully explored PCa immune microenvironment. This …

[HTML][HTML] Prognostic value of genes and immune infiltration in prostate tumor microenvironment

W Sun, H Shi, Z Yuan, L Xia, X Xiang, X Quan… - Frontiers in …, 2020 - frontiersin.org
Background Prostate cancer (PCa) is one of the most common cancers and the fifth leading
cause of cancer-related death in men. Immune responses in the tumor microenvironment …

Immune microenvironment infiltration landscape and immune-related subtypes in prostate cancer

W Wu, X Wang, W Le, C Lu, H Li, Y Zhu… - Frontiers in …, 2023 - frontiersin.org
Background The tumor microenvironment (TME) primarily comprises cancer cells, cancer-
infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting …

Immune-related genes are prognostic markers for prostate cancer recurrence

M Fu, Q Wang, H Wang, Y Dai, J Wang, W Kang… - Frontiers in …, 2021 - frontiersin.org
Background Prostate cancer (PCa) is an immune-responsive disease. The current study
sought to explore a robust immune-related prognostic gene signature for PCa. Methods …

Immune signature driven by ADT-induced immune microenvironment remodeling in prostate cancer is correlated with recurrence-free survival and immune infiltration

X Long, H Hou, X Wang, S Liu, T Diao, S Lai… - Cell death & …, 2020 - nature.com
Androgen deprivation therapy (ADT) is a cornerstone treatment for locally advanced or
metastatic prostate cancer (PCa). However, its potential effects on the tumor immune …

[HTML][HTML] The landscape of immune cells infiltrating in prostate cancer

Z Wu, H Chen, W Luo, H Zhang, G Li, F Zeng… - Frontiers in …, 2020 - frontiersin.org
Background This study was to explore the infiltration pattern of immune cells in the prostate
cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune …

Comprehensive analysis and identification of an immune-related gene signature with prognostic value for prostate cancer

Y Zhang, Y Fu - International Journal of General Medicine, 2021 - Taylor & Francis
Background The tumor microenvironment (TME) has recently been proven to play a crucial
role in the development and prognosis of tumors. However, the current knowledge on the …

Immune-related gene-based novel subtypes to establish a model predicting the risk of prostate cancer

E Zhang, J He, H Zhang, L Shan, H Wu, M Zhang… - Frontiers in …, 2020 - frontiersin.org
Background There is significant heterogeneity in prostate cancer (PCa), but immune status
can reflect its prognosis. This study aimed to explore immune-related gene-based novel …

[HTML][HTML] Identification of biomarkers for immunotherapy response in prostate cancer and potential drugs to alleviate immunosuppression

J Zhang, X Ding, K Peng, Z Jia, J Yang - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Background: Immunotherapy has a significant effect on the treatment of many tumor types.
However, prostate cancers generally fail to show significant responses to immunotherapy …

A novel gene signature to predict immune infiltration and outcome in patients with prostate cancer

N Shao, H Tang, Y Mi, Y Zhu, F Wan, D Ye - Oncoimmunology, 2020 - Taylor & Francis
Prostate cancer (PCa) is one of the most common malignancies in male. We aim to establish
a novel gene signature for immune infiltration and outcome (biochemical recurrence (BCR) …