Revised Manuscript Received April 5, 1994® abstract: Phosphorylation-mediated regulation
of voltage-gated K+ channels has been implicated in numerous electrophysiological studies; …

We have recently shown that the rat brain Kv1. 1 (RCK1) voltage-gated K+ channel is
partially phosphorylated in its basal state in Xenopus oocytes and can be further …

We have isolated and characterized a human cDNA (HBK2) that is homologous to novel
member (RCK2) of the K+ channel RCK gene family expressed in rat brain. RCK2 mRNA …

A novel member of the RCK family of rat brain K+ channels, called RCK2, has been
sequenced and expressed inXenopus oocytes. The K+ currents were voltage-dependent …

Cloning and sequencing of cDNAs isolated from a rat cortex cDNA library reveals that a
gene family encodes several highly homologous K+ channel forming (RCK) proteins …

Extracellular potassium concentration is actively maintained within narrow limits in all higher
organisms. Slight variations in extracellular potassium levels can induce major alterations of …

The modulation by protein kinase C (PKC) of the RCK1 K+ channel was investigated in
Xenopus oocytes by integration of two‐electrode voltage clamp, site‐directed mutagenesis …

Ionic currents in C6 astrocytoma cells were studied using the patch clamp technique under
the whole cell configuration. A delayed rectifier K+ current with an amplitude of∼ 1 nA at+ …

Five distinct K+ channel cDNA molecules (RK1 to RK5) were cloned from either rat heart or
rat aorta cDNA libraries. Four of the channels, RK1 to RK4, are similar or identical to Shaker …

We have cloned a cDNA (RMK2) coding for a Shaker type delayed rectifier K+ channel from
a rat skeletal muscle cDNA library. The clone encodes a putative protein of 602 amino acids …