Development of O/W nanoemulsions for ophthalmic administration of timolol

M Gallarate, D Chirio, R Bussano, E Peira… - International journal of …, 2013 - Elsevier
After an initial screening of ingredients and production methods, nanoemulsions for ocular
administration of timolol containing the drug as maleate (TM) or as ion-pair with AOT …

Development and Evaluation of Diclofenac Sodium Loaded-N-Trimethyl Chitosan Nanoparticles for Ophthalmic Use

R Asasutjarit, T Theerachayanan, P Kewsuwan… - Aaps Pharmscitech, 2015 - Springer
The ophthalmic preparation of diclofenac sodium (DC) for relieving ocular inflammation is
presently available in the market only as an eye drop solution. Due to its low occular …

Engineering of polymer–surfactant nanoparticles of doxycycline hydrochloride for ocular drug delivery

V Pokharkar, V Patil, L Mandpe - Drug delivery, 2015 - Taylor & Francis
Context: Physiologic barriers of the eye, short precorneal drug residence time and poor
corneal penetration are the few reasons for reduced ocular bioavailability. Objective: This …

The impact of R-801 nanoparticles as a long acting topical Glaucoma therapy

MM Ibrahim, MM Jablonski - Journal of Biomedical …, 2019 - ingentaconnect.com
Primary open angle glaucoma (POAG) is the most common glaucoma type worldwide. The
most significant risk factor of this type of glaucoma is the increased intraocular pressure …

[HTML][HTML] Ciprofloxacin-loaded zein/hyaluronic acid nanoparticles for ocular mucosa delivery

TA Jacinto, B Oliveira, SP Miguel, MP Ribeiro… - Pharmaceutics, 2022 - mdpi.com
Bacterial conjunctivitis is a worldwide problem that, if untreated, can lead to severe
complications, such as visual impairment and blindness. Topical administration of …

Novel chitosan-coated niosomal formulation for improved management of bacterial conjunctivitis: a highly permeable and efficient ocular nanocarrier for azithromycin

HM Eid, IA Naguib, RI Alsantali, I Alsalahat… - Journal of …, 2021 - Elsevier
In the present study, we aimed to formulate, optimize, and characterize azithromycin
chitosan coated niosomes (AZM-CTS-NSM) as a novel colloidal system that increases …

Thermosensitive chitosan-gelatin-based hydrogel containing curcumin-loaded nanoparticles and latanoprost as a dual-drug delivery system for glaucoma treatment

YH Cheng, YC Ko, YF Chang, SH Huang… - Experimental eye …, 2019 - Elsevier
Elevated intraocular pressure (IOP) in glaucoma is due to impairment of aqueous humor
drainage via the uveoscleral or trabecular outflow pathway. Latanoprost reduces IOP by …

Hyaluronic acid modified chitosan nanoparticles for effective management of glaucoma: development, characterization, and evaluation

S Wadhwa, R Paliwal, SR Paliwal… - Journal of drug …, 2010 - Taylor & Francis
In clinical practices, solution of dorzolamide hydrochloride (DH) and timolol maléate (TM) is
recommended for the treatment of glaucoma. However, low drug-contact time and poor …

Mucoadhesive dexamethasone acetate-polymyxin B sulfate cationic ocular nanoemulsion–novel combinatorial formulation concept

RH Müller, CM Keck… - Die Pharmazie-An …, 2016 - ingentaconnect.com
Dexamethasone acetate (DEX) and polymyxin B sulfate (polymyxin B) were formulated as a
cationic nanoemulsion for the treatment of ophthalmic infections. As novel concept, the …

[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …