Application of biocompatible nanocarriers in glaucoma: challenges and advances

AK Sah, N Bhuwane, I Choudhary, S Ramkar… - … in Human Health …, 2020 - Springer
Glaucoma is a serious and complex eye disorder with worldwide occurrence in the aging
societies and if left untreated at a precise time may lead to the irreversible loss of vision …

[HTML][HTML] Design of topical ocular ciprofloxacin nanoemulsion for the management of bacterial keratitis

AAA Youssef, C Cai, N Dudhipala, S Majumdar - Pharmaceuticals, 2021 - mdpi.com
Bacterial keratitis (BK) is a critical ocular infection that can lead to serious visual disability.
Ciprofloxacin (CIP), moxifloxacin (MOX), and levofloxacin (LFX) have been accepted as …

Characterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles

F Li, Y Wen, Y Zhang, K Zheng, J Ban… - Artificial Cells …, 2019 - Taylor & Francis
Abstract Aim 2-HP-β-cyclodextrin-PLGA nanoparticle complexes were prepared to enhance
the aqueous humour delivery of Triamcinolone acetonide. Materials & methods Drug-loaded …

Hybrid dendrimer hydrogel/poly (lactic-co-glycolic acid) nanoparticle platform: an advanced vehicle for topical delivery of antiglaucoma drugs and a likely solution to …

H Yang, CT Leffler - Journal of ocular pharmacology and …, 2013 - liebertpub.com
Glaucoma therapy typically begins with topical medications, of which there are 4 major
classes in common use in the United States: beta-adrenergic antagonists, alpha-agonists …

Nanotechnology for transcorneal drug targeting in glaucoma: challenges and progress

A Zafar, J Ahmad, S Akhter, RT Addo - Ocular drug delivery: advances …, 2016 - Springer
The eye is a highly protected organ, and designing ocular formulation for effective therapy, is
challenging for drug delivery researcher. The anatomical and physiological barriers resulted …

[HTML][HTML] Design of eudragit RL nanoparticles by nanoemulsion method as carriers for ophthalmic drug delivery of ketotifen fumarate

S Soltani, P Zakeri-Milani… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Objective (s): Ketotifen fumarate (KF) is a selective and noncompetitive histamine antagonist
(H1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and …

Brinzolamide–loaded nanoemulsions: ex vivo transcorneal permeation, cell viability and ocular irritation tests

MM Mahboobian, A Seyfoddin… - Pharmaceutical …, 2019 - Taylor & Francis
The aim of this study was to investigate the corneal penetration of brinzolamide (BZ)
nanoemulsions (NEs) and evaluate their in vitro and ex vivo irritancy potential. Twelve BZ …

Development, optimization and characterization of ocular nanoemulsion of an antifungal agent using design of experiments

M Macwan, B Prajapati - Research Journal of Pharmacy and …, 2022 - indianjournals.com
Antifungal agents of the echinocandin family act on the fungal cell wall by inhibition of
synthesis of β (1, 3)-D-glucan. Currently no market formulation is available for ocular …

QbD based development of resveratrol-loaded mucoadhesive lecithin/chitosan nanoparticles for prolonged ocular drug delivery

M Saha, DR Saha, T Ulhosna, SM Sharker… - Journal of Drug Delivery …, 2021 - Elsevier
The lower drug retention to the eye's anterior portion is a prime concern in the ocular drug
delivery system. To improve the drug retention capacity, we aimed to develop drug …

Overview on ocular drug delivery through colloidal nano-suspension

P Jaiswal, A Mishra, D Kesharwani… - Research Journal of …, 2023 - indianjournals.com
Over the last few years, the focus over the ocular delivery system has been increased
exponentially. The reason behind this interest may be due to noninvasive nature of this …