Glycointeractome of Neisseria gonorrhoeae: identification of host glycans targeted by the gonococcus to facilitate adherence to cervical and urethral epithelial cells
EA Semchenko, AV Everest-Dass, FEC Jen… - MBio, 2019 - Am Soc Microbiol
Neisseria gonorrhoeae is a significant threat to global health for which a vaccine and novel
treatment options are urgently needed. Glycans expressed by human cells are commonly …
treatment options are urgently needed. Glycans expressed by human cells are commonly …
[HTML][HTML] Intimate relations: molecular and immunologic interactions between Neisseria gonorrhoeae and HIV-1
While the global incidence of human immunodeficiency virus (HIV-1) remains well above
UNAIDS targets, sexual transmission HIV is surprisingly inefficient. A variety of host, viral …
UNAIDS targets, sexual transmission HIV is surprisingly inefficient. A variety of host, viral …
[HTML][HTML] Inhibition of Wnt Signaling Pathways Impairs Chlamydia trachomatis Infection in Endometrial Epithelial Cells
J Kintner, CG Moore, JD Whittimore… - Frontiers in Cellular …, 2017 - frontiersin.org
Chlamydia trachomatis infections represent the predominant cause of bacterial sexually
transmitted infections. As an obligate intracellular bacterium, C. trachomatis is dependent on …
transmitted infections. As an obligate intracellular bacterium, C. trachomatis is dependent on …
Preclinical testing of vaccines and therapeutics for gonorrhea in female mouse models of lower and upper reproductive tract infection
KL Connolly, M Pilligua-Lucas, C Gomez… - The Journal of …, 2021 - academic.oup.com
Murine models of Neisseria gonorrhoeae lower reproductive tract infection are valuable
systems for studying N. gonorrhoeae adaptation to the female host and immune responses …
systems for studying N. gonorrhoeae adaptation to the female host and immune responses …
Role of the gonococcal neisserial heparin binding antigen in microcolony formation, and serum resistance and adherence to epithelial cells
The sexually transmitted infection gonorrhoea is on the rise worldwide and an increased
understanding of the mechanisms of colonization and pathogenesis of Neisseria …
understanding of the mechanisms of colonization and pathogenesis of Neisseria …
[HTML][HTML] Neisseria gonorrhoeae MlaA influences gonococcal virulence and membrane vesicle production
BI Baarda, RA Zielke, A Le Van, AE Jerse… - Plos …, 2019 - journals.plos.org
The six-component maintenance of lipid asymmetry (Mla) system is responsible for
retrograde transport of phospholipids, ensuring the barrier function of the Gram-negative cell …
retrograde transport of phospholipids, ensuring the barrier function of the Gram-negative cell …
Cytoskeleton and motor proteins are required for the transcytosis of Neisseria gonorrhoeae through polarized epithelial cells
Neisseria gonorrhoeae interact with polarized T84 epithelial cells by engaging
carcinoembryonic antigen-related cellular adhesion molecule (CEACAM) receptors …
carcinoembryonic antigen-related cellular adhesion molecule (CEACAM) receptors …
Biology of Neisseria gonorrhoeae and the Clinical Picture of Infection
CA Ison - Sexually transmitted infections and sexually transmitted …, 2011 - Springer
Neisseria gonorrhoeae is the causative bacterium of gonorrhoea, the second most common
bacterial sexually transmitted infection (STI). It is an obligate human pathogen and colonises …
bacterial sexually transmitted infection (STI). It is an obligate human pathogen and colonises …
Infection of mucosal epithelial cells by Neisseria gonorrhoeae
JPM van Putten, TD Duensing - Reviews and Research in …, 1997 - journals.lww.com
The bacterial pathogen Neisseria gonorrhoeae (gonococcus) is able to colonize and
penetrate the human mucosa, to avoid the host's defences and to persist in various …
penetrate the human mucosa, to avoid the host's defences and to persist in various …
Distinct effects of the cervicovaginal microbiota and herpes simplex type 2 infection on female genital tract immunology
B Shannon, P Gajer, TJ Yi, B Ma… - The Journal of …, 2017 - academic.oup.com
Background. Genital inflammation is a key determinant of human immunodeficiency virus
(HIV) transmission, and may increase HIV-susceptible target cells and alter epithelial …
(HIV) transmission, and may increase HIV-susceptible target cells and alter epithelial …