The newly emerged coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) that caused the COVID-19 pandemic, is the closest relative of SARS-CoV with high …

Emerging outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection is a major threat to public health. The morbidity is increasing due to lack of SARS …

Neutrophil elastase (NE) is a major inflammatory mediator in cystic fibrosis (CF) that is a
robust predictor of lung disease progression. NE directly causes airway injury via protease …

The epidemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has now spread worldwide and efficacious …

SARS-CoV-2 is the viral pathogen causing the COVID19 global pandemic. Consequently,
much research has gone into the development of preclinical assays for the discovery of new …

The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute
infection of the respiratory tract (COVID-19) that can result in severe disease and lethality …

Elafin is a neutrophil serine protease inhibitor expressed in lung and displaying anti-
inflammatory and anti-bacterial properties. Previous studies demonstrated that some innate …

Cathepsin S (Cat S) is predominantly expressed in antigen-presenting cells and is up-
regulated in several preclinical models of antigen-induced inflammation, suggesting a role …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins interact with
the eukaryotic translation machinery, and inhibitors of translation have potent antiviral …

SARS-CoV-2 infection begins with the association of its spike 1 (S1) protein with host
angiotensin-converting enzyme-2 (ACE2). Targeting the interaction between S1 and ACE2 …