Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …

Obesity is a common complex trait that elevates the risk for various diseases, including type
2 diabetes and cardiovascular disease. A combination of environmental and genetic factors …

The prevalence of obesity and diabetes, which are heritable traits that arise from the
interactions of multiple genes and lifestyle factors, continues to rise worldwide, causing …

Excessive fat deposition in obesity has a multifactorial aetiology, but is widely considered
the result of disequilibrium between energy intake and expenditure. Despite specific public …

The genetic contribution to interindividual variation in common obesity has been estimated
at 40–70%. Yet, despite a relatively high heritability, the search for obesity susceptibility …

Obesity and its related health complications is a major problem worldwide. Hypothalamus
and their signalling molecules play a critical role in the intervening and coordination with …

Obesity is a global and growing problem. The detrimental health consequences of obesity
are significant and include co-morbidities such as diabetes, cancer and coronary heart …

The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Obesity is a global health problem that is gradually affecting each continent of the world.
Obesity is a heterogeneous disorder, and the biological causes of obesity are complex. The …