Tumour‐suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model
Oestrogen receptor β (ERβ) has been suggested to have anti‐proliferative and anti‐tumour
effects in breast and prostate cancer cells, but other studies have indicated its tumour …
effects in breast and prostate cancer cells, but other studies have indicated its tumour …
Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells
K Edvardsson, A Ström, P Jonsson… - Molecular …, 2011 - academic.oup.com
Several studies suggest estrogen to be protective against the development of colon cancer.
Estrogen receptor β (ERβ) is the predominant estrogen receptor expressed in colorectal …
Estrogen receptor β (ERβ) is the predominant estrogen receptor expressed in colorectal …
ERβ is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components
V Martineti, L Picariello, I Tognarini… - Endocrine-related …, 2005 - erc.bioscientifica.com
Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …
development of colon cancer through indirect and direct effects on colonic epithelium …
[HTML][HTML] Association of the oestrogen receptor beta with hormone status and prognosis in a cohort of female patients with colorectal cancer
G Topi, R Ehrnström, K Jirström, I Palmquist… - European journal of …, 2017 - Elsevier
Background The oestrogen receptor beta (ERβ) is the predominant oestrogen receptor in
the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic …
the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic …
High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer
In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …
Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation
PA Konstantinopoulos, A Kominea, G Vandoros… - European journal of …, 2003 - Elsevier
Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …
Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells
O Treeck, E Diepolder, M Skrzypczak… - BMC cancer, 2019 - Springer
Background Estrogen receptor β (ERβ) has been repeatedly suggested to play important
roles in hormone-dependent cancer like in tumors of the breast, ovary or prostate. In this …
roles in hormone-dependent cancer like in tumors of the breast, ovary or prostate. In this …
Estrogen receptors in colorectal cancer: goalkeepers, strikers, or bystanders?
J Hartman, JÅ Gustafsson - Cancer Prevention Research, 2010 - AACR
This perspective on Jin et al.(beginning on page 910 in this issue of the journal) discusses
the importance of estrogen signaling in colorectal carcinogenesis, with a focus on estrogen …
the importance of estrogen signaling in colorectal carcinogenesis, with a focus on estrogen …
Targeting estrogen receptors in colorectal cancer
JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
Hormones have become a useful therapeutic aspect of clinical endocrinology but how to use
them to optimize the health benefits and avoid adverse effects is a major challenge …
them to optimize the health benefits and avoid adverse effects is a major challenge …
Expression of oestrogen receptor β and prognosis of colorectal cancer
A Rudolph, C Toth, M Hoffmeister, W Roth… - British journal of …, 2012 - nature.com
Background: Previous studies suggest that sex steroids influence colorectal cancer (CRC)
carcinogenesis. The oestrogen receptor β (ERβ) is the predominantly expressed ER in the …
carcinogenesis. The oestrogen receptor β (ERβ) is the predominantly expressed ER in the …
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