Osteoarthritis (OA) causes severe and functional dysfunction due to abnormal inflammation.
The objective of this study was to evaluate the effect of Harpagide (HPG) on TNF-α-induced …

There is growing evidence in support of the involvement of inflammatory response in the
pathogenesis of osteoarthritis (OA). Harpagoside, one of the bioactive components of …

This study aimed to determine whether hesperetin (HPT) has chondroprotective effects
against the TNF-α-induced inflammatory response of chondrocytes and related mechanisms …

Gypenoside (GP), the main active ingredient of Gynostemma pentaphyllum, possesses a
variety of pharmacological capacities including anti‐inflammation, anti‐oxidation, and anti …

Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that
causes local bone erosion and systemic osteoporosis. Harpagoside (HAR), an iridoid …

Osteoarthritis (OA) is a joint pain and dysfunction syndrome resulting from severe joint
degeneration. Inflammation and degeneration of the articular cartilage are two main features …

The endocannabinoid system is involved in the nociceptive and anti-inflammatory pathways,
and a lowered expression of CB2 receptors has been associated with inflammatory …

Objective This study aimed to evaluate glycolysis inhibitor which can effectively ameliorate
arthritis by inhibiting synoviocyte activation through AMPK/NF-кB pathway in AA rats …

Osteoarthritis (OA) is driven by chronic low-grade inflammation and subsequent cartilage
degradation. OA is the most prevalent degenerative joint disease worldwide, and its …

Osteoarthritis (OA) is primarily characterized by progressive degeneration and destruction of
articular cartilage. Currently, there is no effective method to treat OA. The metabolic …