Introduction: Currently, five pharmacotherapeutic options are available to treat Alzheimer's
disease: memantine; the three cholinesterase inhibitors donepezil, galantamine, and …

Although the underlying pathogenesis of Alzheimer's disease (AD) is not fully understood,
one of its key features is the widespread loss of central cholinergic innervation, known to be …

Background There is no cure for dementia, and no treatments exist to halt or reverse the
course of the disease. Treatments are aimed at improving cognitive and functional …