The pleiotropic functions of the Y‐box‐binding protein, YB‐1

K Kohno, H Izumi, T Uchiumi, M Ashizuka… - …, 2003 - Wiley Online Library
The Y‐box‐binding protein (YB‐1) represents the most evolutionary conserved nucleic‐acid‐
binding protein currently known. YB‐1 is a member of the cold‐shock domain (CSD) protein …

YB‐1 protein: functions and regulation

DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …

The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1

CPAM Kloks, CAEM Spronk, E Lasonder… - Journal of molecular …, 2002 - Elsevier
The human Y-box protein 1 (YB-1) is a member of the Y-box protein family, a class of
proteins involved in transcriptional and translational regulation of a wide range of genes …

[HTML][HTML] Crystal structure of a Y-box binding protein 1 (YB-1)–RNA complex reveals key features and residues interacting with RNA

XJ Yang, H Zhu, SR Mu, WJ Wei, X Yuan… - Journal of Biological …, 2019 - ASBMB
The Y-box binding protein 1 (YB-1) is a member of the cold shock domain (CSD) protein
family and is recognized as an oncogenic factor in several solid tumors. By binding to RNA …

A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance

A Alkrekshi, W Wang, PS Rana, V Markovic… - Cellular signalling, 2021 - Elsevier
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …

[HTML][HTML] Nuclear translocation of the Y-box binding protein by ultraviolet irradiation

K Koike, T Uchiumi, T Ohga, S Toh, M Wada, K Kohno… - FEBS letters, 1997 - Elsevier
The Y-box binding protein, YB-1, is a member of a DNA binding protein family with a
structurally and functionally conserved cold shock domain. Using Western blotting and …

[HTML][HTML] YB-1 as an oncoprotein: functions, regulation, post-translational modifications, and targeted therapy

Q Yin, M Zheng, Q Luo, D Jiang, H Zhang, C Chen - Cells, 2022 - mdpi.com
Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …

Proteasome‐mediated cleavage of the Y‐box‐binding protein 1 is linked to DNA‐damage stress response

AV Sorokin, AA Selyutina, MA Skabkin… - The EMBO …, 2005 - embopress.org
YB‐1 is a DNA/RNA‐binding nucleocytoplasmic shuttling protein whose regulatory effect on
many DNA‐and RNA‐dependent events is determined by its localization in the cell …

YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescence

ZH Lu, JT Books, TJ Ley - Molecular and cellular biology, 2005 - Taylor & Francis
Proteins containing “cold shock” domains belong to the most evolutionarily conserved family
of nucleic acid-binding proteins known among bacteria, plants, and animals. One of these …

Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells

Y Basaki, F Hosoi, Y Oda, A Fotovati, Y Maruyama… - Oncogene, 2007 - nature.com
Abstract Y-box-binding protein 1 (YB-1), which is a member of the DNA-binding protein
family containing a cold-shock domain, has pleiotropic functions in response to various …