Y-box binding protein-1 (YB-1) plays pivotal roles in acquisition of global drug resistance
and cell growth promotion through transcriptional activation of genes for both drug …

The Y-box binding protein (YB-1) is known to be a multifunctional transcription and
translation factor during expression of several proteins. It is a vital oncoprotein that regulates …

Three cold shock domain (CSD) family members (YB-1, MSY2, and MSY4) exist in
vertebrate species ranging from frogs to humans. YB-1 is expressed throughout …

Nuclear localization and high levels of the Y-box binding protein YB1 appear to be important
indicators of drug resistance and tumor prognosis. YB1 also interacts with the p53 tumor …

The p53 tumor suppressor plays a major role in preventing tumor development by
transactivating genes to remove or repair potentially tumorigenic cells. Here we show that …

The Y-box binding protein, YB-1, belongs to a family of multifunctional proteins which
regulate gene expression on both transcriptional and translational levels. The tumor …

Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …

YB-1 protein levels are elevated in most human breast cancers, and high YB-1 levels have
been correlated with drug resistance and poor clinical outcome. YB-1 is a stress-responsive …

YB-1 is a member of a newly defined family of DNA-and RNA-binding proteins, the Y box
factors. These proteins have been shown to affect gene expression at both the …

Nuclear localization and high levels of the Y-box-binding protein YB1 appear to be important
indicators of drug resistance and tumor prognosis. YB1 also interacts with the p53 tumor …