EpiDiverse Toolkit: a pipeline suite for the analysis of bisulfite sequencing data in ecological plant epigenetics

A Nunn, SN Can, C Otto, M Fasold… - NAR genomics and …, 2021 - academic.oup.com
The expanding scope and scale of next generation sequencing experiments in ecological
plant epigenetics brings new challenges for computational analysis. Existing tools built for …

Epigenetic approaches in non-model plants

MT Boquete, NCAM Wagemaker, P Vergeer… - Plant epigenetics and …, 2020 - Springer
Reduced representation bisulfite sequencing is an emerging methodology for evolutionary
and ecological genomics and epigenomics research because it provides a cost-effective …

The EpiDiverse plant epigenome-wide association studies (EWAS) pipeline

SN Can, A Nunn, D Galanti, D Langenberger, C Becker… - Epigenomes, 2021 - mdpi.com
Bisulfite sequencing is a widely used technique for determining DNA methylation and its
relationship with epigenetics, genetics, and environmental parameters. Various techniques …

Approaches to whole-genome methylome analysis in plants

X Yang, SA Mackenzie - Plant Epigenetics and Epigenomics: Methods and …, 2020 - Springer
Cytosine methylation as a reversible chromatin mark has been investigated extensively for
its influence on gene silencing and the regulation of its dynamic association–disassociation …

Performance of mapping approaches for whole-genome bisulfite sequencing data in crop plants

C Grehl, M Wagner, I Lemnian, B Glaser… - Frontiers in plant …, 2020 - frontiersin.org
DNA methylation is involved in many different biological processes in the development and
well-being of crop plants such as transposon activation, heterosis, environment-dependent …

Population epigenetics: DNA methylation in the plant omics era

J Liu, X Zhong - Plant Physiology, 2024 - academic.oup.com
DNA methylation plays an important role in many biological processes. The mechanisms
underlying the establishment and maintenance of DNA methylation are well understood …

Evaluation of MeDIP-Chip in the Context of Whole-Genome Bisulfite Sequencing (WGBS-Seq) in Arabidopsis

R Wardenaar, H Liu, V Colot, M Colomé-Tatché… - Tiling Arrays: Methods …, 2013 - Springer
Studies of DNA methylation in Arabidopsis have rapidly advanced from the analysis of a
single reference accession to investigations of large populations. The goal of emerging …

Detection of somatic epigenetic variation in Norway spruce via targeted bisulfite sequencing

K Heer, KK Ullrich, M Hiss, S Liepelt… - Ecology and …, 2018 - Wiley Online Library
Epigenetic mechanisms represent a possible mechanism for achieving a rapid response of
long‐lived trees to changing environmental conditions. However, our knowledge on plant …

Covering your bases: inheritance of DNA methylation in plant genomes

CE Niederhuth, RJ Schmitz - Molecular plant, 2014 - cell.com
Cytosine methylation is an important base modification that is inherited across mitotic and
meiotic cell divisions in plant genomes. Heritable methylation variants can contribute to …

MethylScore, a pipeline for accurate and context-aware identification of differentially methylated regions from population-scale plant whole-genome bisulfite …

P Hüther, J Hagmann, A Nunn, I Kakoulidou… - Quantitative Plant …, 2022 - cambridge.org
Whole-genome bisulfite sequencing (WGBS) is the standard method for profiling DNA
methylation at single-nucleotide resolution. Different tools have been developed to extract …