[HTML][HTML] Caution about early intubation and mechanical ventilation in COVID-19

MJ Tobin, F Laghi, A Jubran - Annals of intensive care, 2020 - Springer
Some experts have argued that mechanical ventilation should be employed early in order to
prevent COVID-19 patients progressing from mild disease to more severe lung injury. This …

[HTML][HTML] P-SILI is not justification for intubation of COVID-19 patients

MJ Tobin, F Laghi, A Jubran - Annals of Intensive Care, 2020 - Springer
They are correct in observing we quoted opinion articles: three were by Gattinoni et al. We
will not point out all instances where Gattinoni et al. misquoted our article, but two need to be …

[HTML][HTML] Noninvasive respiratory support and patient self-inflicted lung injury in COVID-19: a narrative review

D Battaglini, C Robba, L Ball, PL Silva, FF Cruz… - British Journal of …, 2021 - Elsevier
COVID-19 pneumonia is associated with hypoxaemic respiratory failure, ranging from mild
to severe. Because of the worldwide shortage of ICU beds, a relatively high number of …

[HTML][HTML] Spontaneous breathing, transpulmonary pressure and mathematical trickery

L Gattinoni, JJ Marini, M Busana, D Chiumello… - Annals of Intensive …, 2020 - Springer
We read with interest the review by Tobin, Laghi and Jubran on mechanical ventilation in
COVID-19 [1]. Rather than a balanced review of the literature, the authors have chosen their …

[HTML][HTML] High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study

L Weaver, A Das, S Saffaran, N Yehya, TE Scott… - Annals of intensive …, 2021 - Springer
Background There is on-going controversy regarding the potential for increased respiratory
effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing …

Alternatives to invasive ventilation in the COVID-19 pandemic

BK Patel, JP Kress, JB Hall - Jama, 2020 - jamanetwork.com
Since its invention in the 1940s, the positive pressure ventilator has always been known to
have both risks and benefits. Although mechanical ventilation is unquestionably lifesaving …

[HTML][HTML] Mechanical ventilation in COVID-19: interpreting the current epidemiology

H Wunsch - American Journal of Respiratory and Critical Care …, 2020 - atsjournals.org
The world is scrutinizing every cohort and every outcome for patients with coronavirus
disease (COVID-19), particularly the most critically ill who are receiving mechanical …

[HTML][HTML] Ventilation of COVID-19 patients in intensive care units

S Möhlenkamp, H Thiele - Herz, 2020 - Springer
About 5–15% of patients with COVID (corona virus disease)-19 infection require intensive
care surveillance and ventilatory support. Current recommendations suggest early …

Continuous positive airway pressure to avoid intubation in SARS-CoV-2 pneumonia: a two-period retrospective case-control study

M Oranger, J Gonzalez-Bermejo… - European …, 2020 - Eur Respiratory Soc
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause severe
pneumonia requiring invasive mechanical ventilation [1], in the context of atypical acute …

[HTML][HTML] Rethinking the early intubation paradigm of COVID-19: time to change gears?

P Rola, J Farkas, R Spiegel, C Kyle-Sidell… - Clinical and …, 2020 - ncbi.nlm.nih.gov
The 21st century's first true pandemic has taken the world by storm in the first months of
2020. Originating in Wuhan, China, the severe acute respiratory syndrome coronavirus 2 …