Acute megakaryoblastic leukemia is a rare variant of acute myeloid leukemia, whereby
leukemic blasts display characteristic morphologic and phenotypic features indicating …

Rearrangements of the mixed-lineage leukemia (MLL) gene have been associated with a
poor prognosis in infant acute lymphoblastic leukemia (ALL). Previously, MLL translocations …

Objectives This study assesses the clinical significance of additional cytogenetic
abnormalities (ACAs) and/or the deletion of 3′ CBFB (3′ CBFB del) resulting in …

Giant cytoplasmic inclusions in myeloid precursors or myeloblasts, similar those seen in the
Chediak-Higashi Syndrome, are called pseudo-Chediak-Higashi inclusions. These giant …

A 4-year-old boy presented with spontaneous hematomas, lower limb pain, fever, and
hepatosplenomegaly. A complete blood count revealed pancytopenia (white blood cells …

Objectives Acute myeloid leukemia (AML) with ETV6:: CHIC2 and basophilia is rare in
hematologic malignancies with poor prognosis. Due to the small number of clinical cases, it …

Acute myeloid leukemia (AML) with inv (16)(p13. 1q22) resulting in CBFB-MYH11 fusion is
associated with a favorable prognosis. The presence of a KIT mutation modifies it to an …

Acute lymphoblastic leukemia is the most common type of childhood cancer worldwide.
Mexico City has one of the highest incidences and mortality rates of this cancer. It has …

Background ZNF384 gene rearrangements with multiple partner genes are recurrent in
acute leukemia and are most often associated with a precursor B cell immunophenotype …

Abstract The t (1; 22)(p13; q13) is a nonrandom chromosomal abnormality in acute leukemia
with the fusion oncogene, RBM15‐MKL1 (OTT‐MAL), identified recently. However, this …