In many types of cancer, tumors metastasize through the lymphatic system to draining lymph
nodes. These sentinel lymph nodes have gained increased attention as a prognostic …

The lymphatic system is a complicated system consisting of the lymphatic vessels and lymph
nodes draining the extracellular fluid containing cellular debris, excess water and toxins to …

This textbook describes in detail the process of cancer metastasis from a single cell in the
primary site through its arduous journey to the sentinel lymph node as the main gateway and …

The sentinel lymph node (SLN) is defined as the lymph node (s) first receiving lymphatic
drainage from the site of the primary tumor. The histopathological status of SLN is one of the …

Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study
of micrometastasis. In eighty percent (80%) of metastasis there lies an orderly pattern of …

Physiologically, the lymphatic system regulates fluid volume in the interstitium and provides
a conduit for immune cells to travel to lymph nodes, but pathologically, the lymphatic system …

The mechanisms by which malignant tumors leave the primary tumor site, invade
lymphatics, and metastasize to regional lymph nodes (RLNs) are complex and interrelated …

The leading cause of breast cancer‐associated death is metastasis. In 80% of solid tumors,
metastasis via the lymphatic system precedes metastasis via the vascular system. However …

In human solid cancer, lymph node status is the most important indicator for clinical
outcome. Recent developments in the sentinel lymph node concept and technology have …

Identification of cancer spread to tumor‐draining lymph nodes offers critical information for
guiding treatment in many cancer types. Current clinical methods of nodal staging are …