Importance Individuals can be classified as being at clinical high risk (CHR) for psychosis if
they meet at least one of the ultra–high-risk (UHR) inclusion criteria (brief limited intermittent …

Background The clinical high-risk state for psychosis (HRP) is associated with an enhanced
probability of developing a psychotic episode over a relatively short period of time. However …

Twenty percent of individuals at clinical high risk for psychosis (CHR-P) develop the disorder
within 2 years. Extensive research has explored the factors that differentiate those who …

The validity and clinical utility of the concept of “clinical high risk”(CHR) for psychosis have
so far been investigated only in risk‐enriched samples in clinical settings. In this population …

Importance Pretest risk estimation is routinely used in clinical medicine to inform further
diagnostic testing in individuals with suspected diseases. To our knowledge, the overall …

Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Recent evidence has suggested that psychosis could develop not only in people at clinical
high risk for psychosis (CHR-P) but also in those with clinical risk syndromes for emergent …

(1) The consistency and magnitude of the prevalence of Clinical High-Risk for Psychosis
(CHR-P) individuals are undetermined, limiting efficient detection of cases. We aimed to …

Aims The clinical outcomes of individuals at clinical high risk of psychosis (CHR-P) who do
not transition to psychosis are heterogeneous and inconsistently reported. We aimed to …

Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …