Effect of regional DNA methylation on gene expression.
I Keshet, J Yisraeli, H Cedar - Proceedings of the National …, 1985 - National Acad Sciences
The effect of DNA methylation on the transcriptional activity of the hamster adenine
phosphoribosyltransferase (aprt) and the herpes thymidine kinase (tk) genes has been …
phosphoribosyltransferase (aprt) and the herpes thymidine kinase (tk) genes has been …
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.
R Stein, A Razin, H Cedar - Proceedings of the National …, 1982 - National Acad Sciences
The effect of DNA methylation on the expression of the hamster adenine
phosphoribosyltransferase (aprt) gene in mouse cells has been examined. This gene was …
phosphoribosyltransferase (aprt) gene in mouse cells has been examined. This gene was …
DNA methylation and gene activity.
H Cedar - Cell, 1988 - europepmc.org
The above experiments support a relatively simple model to explain the role of DNA
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …
DNA methylation—a regulatory signal in eukaryotic gene expression
W Doerfler - Journal of General Virology, 1981 - microbiologyresearch.org
There are at least two systems in which inhibitory effects of DNA modification on DNA-
protein interactions have been unambiguously demonstrated.(i) At sequences specifically …
protein interactions have been unambiguously demonstrated.(i) At sequences specifically …
DNA methylation has a local effect on transcription and histone acetylation
RA Irvine, IG Lin, CL Hsieh - Molecular and cellular biology, 2002 - Taylor & Francis
DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …
deacetylation and DNA methylation has been established. However, the transcriptional …
[图书][B] DNA methylation: molecular biology and biological significance
J Jost, H Saluz - 2013 - books.google.com
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …
Effects of DNA methylation on DNA-binding proteins and gene expression
PH Tate, AP Bird - Current opinion in genetics & development, 1993 - Elsevier
DNA methyltransferase is needed for normal development, perhaps because DNA
methylation plays a part in the control of gene activity. It is clear that the methylation of …
methylation plays a part in the control of gene activity. It is clear that the methylation of …
Gene methylation patterns and expression
J Yisraeli, M Szyf - DNA methylation: biochemistry and biological …, 1984 - Springer
Three basic approaches have been employed in the study of the effect of DNA methylation
of particular genes on their expression. One approach uses chemicals that cause …
of particular genes on their expression. One approach uses chemicals that cause …
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter.
F Watt, PL Molloy - Genes & development, 1988 - genesdev.cshlp.org
Cytosine methylation within CpG dinucleotides has been implicated in the regulation of
gene expression in vertebrates and, in some cases, has been shown to be causative in …
gene expression in vertebrates and, in some cases, has been shown to be causative in …
Understanding the molecular mechanism by which methylation influences gene expression.
WS Dynan - 1989 - cabidigitallibrary.org
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