The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

Carbapenem resistance in Gram-negative bacteria has come into sight as a serious global
threat. Carbapenem-resistant Gram-negative pathogens and their main representatives …

Purpose To describe the current standards of care and major recent advances with regard to
antimicrobial resistance (AMR) and to give a prospective overview for the next 30 years in …

Infections due to carbapenem-resistant Gram-negative bacteria are burdened by high
mortality and represent an urgent threat to address. Clinicians are currently at a dawn of a …

Antimicrobial resistance in pathogenic gram-negative bacteria is one of the most pressing
challenges in the field of infectious diseases and is one of 4 key areas of unmet medical …

Emerging antibiotic resistance has created a major public health dilemma, compounded by
a dearth of new antibiotic options. Multidrug-resistant Gram-negative organisms have …

Gram-negative bacteria are the dominant killers among bacterial pathogens in the intensive
care unit. Antibiotic resistance has become a threat in hospital settings and efforts are being …

Antibiotics are among the most important discoveries of the 20th century, having saved
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …

Antibiotics primarily act on bacterial growth by eliminating bacteria or preventing them from
reproducing and spreading [1, 2]. However, because they do so at different rates, the …

Antimicrobial therapy transformed medical practice from a merely diagnosis-focused
approach 80 years ago to a treatment-focused approach, saving millions of lives in the years …