Background Approximately, one-third to one-half of children with chronic granulomatous
disease (CGD) develop gastrointestinal inflammation characteristic of idiopathic …

Background: Family history provides important information on risk of developing
inflammatory bowel disease [IBD], and genetic profiling of first-degree relatives [FDR] of …

Abstract Background and Aims Inflammatory bowel disease [IBD] phenotypes are very
heterogeneous between patients, and current clinical and molecular classifications do not …

Background Crohn's disease (CD) and ulcerative colitis (UC) are two major forms of
inflammatory bowel disease (IBD). Meta-analyses of genome-wide association studies …

OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) are chronic immunologically
mediated diseases with a progressive relapsing remitting course. There is considerable …

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD), ulcerative colitis
(UC), and unclassified IBD, is characterized by chronic intestinal inflammation and has a …

Background Genetic susceptibility may play a more important role in the etiology of early-
onset inflammatory bowel disease (IBD) than in late-onset IBD, and therefore pediatric-onset …

Inflammatory bowel disease (IBD) is thought to develop as a result of dysregulation of the
immune response to normal gut flora in a genetically susceptible host. Approximately 25% of …

OBJECTIVES: Phenotype characteristics of inflammatory bowel disease (IBD) may differ
significantly among ethnic subpopulations. The aim of this study was to characterize the IBD …

Aim To investigate the association between known inflammatory bowel disease (IBD)-
associated genetic variants and development of paediatric IBD, and specific clinical sub …