BACKGROUND The influence of familial IBD on phenotype and course of disease in
patients with CD and UC has not been studied in population-based cohorts. AIM To …

Background: Crohn's disease (CD) may progress from an inflammatory to a stricturing or
penetrating disease phenotype. The aim of our study was to identify single nucleotide …

Summary Crohn's disease (CD), a type of chronic inflammatory bowel disease (IBD), is
commonly found in European and East Asian countries. The calculated heritability of CD …

Objectives The aim of the study was to evaluate associations between inflammatory bowel
disease (IBD) presentation and variants in NOD2, TLR4, TNF-α, IL-6, IL-1β, and IL-RN …

Summary Background and Aims To estimate familial aggregation of inflammatory bowel
disease (IBD), we performed a nationwide, case–control study and examined the odds for …

Background The observed heritability of inflammatory bowel disease (IBD) is incompletely
explained by known genetic risk factors. Kindred-specific genetic variants that cause IBD …

Abstract Background The NIDDK IBD Genetics Consortium (IBDGC) collects DNA and
phenotypic data from inflammatory bowel disease (IBD) subjects to provide a resource for …

Inflammatory bowel disease (IBD) is a chronic and often debilitating condition that affects
approximately one in 250 individuals in the USA and UK [1]. IBD is thought to arise from an …

If you are picking up this book for the very first time you might be asking yourself why it is
entirely dedicated to the topic of the Molecular Genetics of IBD—or more specifically, why …

We provide a comprehensive field synopsis of genetic and epigenetic associations for
paediatric Inflammatory Bowel Disease (IBD). A systematic review was performed and …