Introduction: Immunosuppression, the cornerstone of management of Crohn's disease (CD)
and ulcerative colitis (UC)(inflammatory bowel diseases; IBD) is associated with an …

Crohn's disease (CD) and ulcerative colitis (UC) are 2 major forms of idiopathic chronic
inflammatory bowel diseases (IBD). Although the pathogenic mechanisms of IBD are …

Introduction or background It has long been recognized from epidemiological data that
inflammatory bowel diseases (IBD), Crohns disease (CD) and ulcerative colitis (UC), have a …

Background Both ulcerative colitis (UC) and Crohn's disease (CD) have a complex etiology
involving multiple genetic and environmental factors. Many genome-wide association …

Twin studies and large-scale population studies have confirmed an increased sibling risk for
both Crohn's disease (CD) and ulcerative colitis (UC). Unlike single gene disorders, CD and …

Background Early-onset disease is frequently examined in genetic studies because it is
presumed to contain a more severe subset of patients under a higher influence of genetic …

The pathogenesis of pediatric inflammatory bowel disease (IBD) is only partially understood.
Strong evidence implicates a strong genetic component including high monozygotic twin …

To the Editor: Whether Crohn's disease (CD) and ulcerative colitis (UC) represent distinct
disorders or comprise a continuum is a key question in inflammatory bowel disease (IBD) …

The two major subtypes of inflammatory bowel disease (IBD), ulcerative colitis (UC, MIM#
191390) and Crohn's disease (CD, MIM# 266600), are chronic relapsing-remitting …

Background Genetic variants make some contributions to inflammatory bowel disease (IBD),
including Crohn's disease (CD) and ulcerative colitis (UC). More than 100 susceptibility loci …