Background An accumulating body of evidence suggests that there is an inverse
relationship between the intake of folate (a water-soluble B-vitamin) and the risk of …

Evidence is growing that low folate status may be a factor in the aetiology of several cancers,
including breast cancer. The methylenetetrahydrofolate reductase gene (MTHFR), which …

Breast cancer is one of the most common malignancies in women worldwide and is
associated with a variety of risk factors. Folate and vitamin B12 are key elements of the one …

Background A growing body of evidence suggests that variations in the levels of folate may
contribute to the development of cancer. A functional polymorphic variant (C→ T substitution …

Accumulating evidence from epidemiologic studies suggests that risk of breast cancer is
reduced in relation to increased consumption of folate and related B vitamins. We …

Background: Evidence from case–control studies suggests that increasing dietary folate
intake is associated with a reduced risk of breast cancer. However, large cohort studies have …

Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one-
carbon metabolism for DNA synthesis and methylation, both are implicated in …

We investigated associations among intake of folate, vitamin B2, vitamin B6, vitamin B12,
and polymorphisms of 5, 10-methylenetetrahydrofolate reductase (MTHFR) and methionine …

We investigated the association between dietary intake of folate, vitamin B6, and the 5, 10-
methylenetetrahydrofolate reductase (MTHFR) genotype with breast cancer. A matched …

Background Several studies have determined that dietary intake of B vitamins may be
associated with breast cancer risk as a result of interactions between 5, 10 …