Eight diabetic subjects with moderately elevated blood pressure (BP)(systolic (SBP) greater
than 140 and/or diastolic (DBP) greater than 90 mmHg) were studied. Each had evidence of …

1. Captopril infused into sodium-loaded dogs produced a fall in both blood pressure [117+/-
9.7 to 96.6+/-11.4 (SD) mmHg] and plasma angiotensin II [11.0+/-3.0 to 1.6+/-1.3 (SD) …

Dose‐response curves of blood pressure and of the biochemical components of the renin‐
angiotensin‐aldosterone system were determined during long‐term treatment with captopril …

Twenty-four patients with moderate to severe hypertension were treated for four weeks with
captopril, an oral inhibitor of angiotensin-converting enzyme. The fall in blood pressure with …

The effects of enalapril, 20 mg orally, on the responses to baroreflex activation and
deactivation by respectively phenylephrine and nitroglycerin were investigated in …

Prolonged low-dose ACTH infusion (5 or 10 iU/24h) leads to a transient increase in plasma
renin activity and angiotensin II concentration in normal man. In order to find out whether the …

To determine the relationship between the early and late hemodynamic effects of captopril in
patients with severe heart failure, we performed serial right heart catheterizations in 51 such …

1. Captopril was shown to be as effective as hydrochlorothiazide in lowering the blood
pressure in patients with moderately severe essential hypertension. 2. With the combination …

The effect of the angiotensin converting enzyme inhibitor ramipril on catecholamine
disposition and noradrenaline reactivity was studied in normotensive volunteers. In the first …

1 Angiotensin (200–500 ng, intravenously) produced a biphasic pressor response
accompanied by reflex bradycardia in rats anaesthetized with sodium pentobarbitone. In …