Handshake of DNA and protein is at the heart of various biological functions occurring
significantly via identification of DNA stretches and structures by proteins. Over recent years …

Transcription factors play essential role in the gene regulation in higher organisms, binding
to multiple target sequences and regulating multiple genes in a complex manner. In order to …

Nucleic acid (NA)–ligand interactions have crucial roles in many cellular processes and,
thus, are increasingly attracting therapeutic interest in drug discovery. Molecular docking is a …

Many structures of protein-DNA complexes have been solved and high-throughput binding
assays were developed because structural biology and genomics researchers were equally …

A huge amount of genetic information is available thanks to the recent advances in
sequencing technologies and the larger computational capabilities, but the interpretation of …

Structural information on interacting proteins is important for understanding life processes at
the molecular level. Genome-wide docking database is an integrated resource for structural …

With the presently available amount of genetic information, a lot of attention focuses on
systems biology and in particular on biomolecular interactions. Considering the huge …

Despite DNA being an important target for several drugs, most of the docking programs are
validated only for proteins and their ligands. In this paper, we used AutoDock 4.0 to perform …