[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

Unravelling the impacts of western-style diets on brain, gut microbiota and cognition

MD Kendig, SJ Leigh, MJ Morris - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The steady rise in the prevalence of obesity has been fostered by modern environments that
reduce energy expenditure and encourage consumption of 'western'-style diets high in fat …

Gut microbiome, inflammation, and cerebrovascular function: link between obesity and cognition

L Olsthoorn, D Vreeken, AJ Kiliaan - Frontiers in Neuroscience, 2021 - frontiersin.org
Obesity affects 13% of the adult population worldwide and this number is only expected to
increase. Obesity is known to have a negative impact on cardiovascular and metabolic …

Overnutrition induced cognitive impairment: insulin resistance, gut-brain axis, and neuroinflammation

Q Zhang, K Jin, B Chen, R Liu, S Cheng… - Frontiers in …, 2022 - frontiersin.org
Overnutrition-related obesity has become a worldwide epidemic, and its prevalence is
expected to steadily rise in the future. It is widely recognized that obesity exerts negative …

Gut to brain dysbiosis: mechanisms linking western diet consumption, the microbiome, and cognitive impairment

EE Noble, TM Hsu, SE Kanoski - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
Consumption of a Western Diet (WD) that is high in saturated fat and added sugars
negatively impacts cognitive function, particularly mnemonic processes that rely on the …

Inflammation and gut-brain axis link obesity to cognitive dysfunction: plausible pharmacological interventions

M Solas, FI Milagro, MJ Ramírez, JA Martínez - Current opinion in …, 2017 - Elsevier
Obesity prevalence is increasing steadily throughout the world's population in most
countries and in parallel the prevalence of metabolic disorders including cardiovascular …

Interplay between the gut-brain axis, obesity and cognitive function

A Agustí, MP García-Pardo, I López-Almela… - Frontiers in …, 2018 - frontiersin.org
Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …

[HTML][HTML] Cognitive decline, dietary factors and gut–brain interactions

B Caracciolo, W Xu, S Collins, L Fratiglioni - Mechanisms of ageing and …, 2014 - Elsevier
Cognitive decline in elderly people often derives from the interaction between aging-related
changes and age-related diseases and covers a large spectrum of clinical manifestations …

The role of the gut microbiome in diet and exercise effects on cognition: a review of the intervention literature

ND Koblinsky, KA Power, L Middleton… - The Journals of …, 2023 - academic.oup.com
Interest in the gut–brain axis and its implications for neurodegenerative diseases, such as
Alzheimer's disease and related dementias, is growing. Microbial imbalances in the …

Obesity and neuroinflammation: a pathway to cognitive impairment

AA Miller, SJ Spencer - Brain, behavior, and immunity, 2014 - Elsevier
Obesity is a growing problem worldwide and is associated with a range of comorbidities,
including cognitive dysfunction. In this review we will address the evidence that obesity and …