Proanthocyanidins attenuated liver damage and suppressed fibrosis in CCl4-treated rats
Liver damage and fibrosis are serious health problems without effective treatment.
Proanthocyanidins (PAs) are flavonoids with several biological effects. We investigated the …
Proanthocyanidins (PAs) are flavonoids with several biological effects. We investigated the …
Anthocyanins isolated from blueberry ameliorates CCl4 induced liver fibrosis by modulation of oxidative stress, inflammation and stellate cell activation in mice
J Sun, Y Wu, C Long, P He, J Gu, L Yang… - Food and Chemical …, 2018 - Elsevier
To study the mechanism of anthocyanins from blueberry on mice model of hepatic fibrosis.
We observed that the levels of serum ALT and AST of 100 mg* kg-1* d-1, 200 mg* kg-1* d-1 …
We observed that the levels of serum ALT and AST of 100 mg* kg-1* d-1, 200 mg* kg-1* d-1 …
Anthocyanins Protect Hepatocytes against CCl4-Induced Acute Liver Injury in Rats by Inhibiting Pro-inflammatory mediators, Polyamine Catabolism, Lipocalin-2, and …
D Popović, G Kocić, V Katić, A Zarubica… - Antioxidants, 2019 - mdpi.com
This study examined the hepatoprotective and anti-inflammatory effects of anthocyanins
from Vaccinim myrtillus (bilberry) fruit extract on the acute liver failure caused by carbon …
from Vaccinim myrtillus (bilberry) fruit extract on the acute liver failure caused by carbon …
Antifibrotic activity of anthocyanidin delphinidin in carbon tetrachloride-induced hepatotoxicity in mice
R Domitrović, H Jakovac - Toxicology, 2010 - Elsevier
The aim of this study was to investigate the hepatoprotective effects of anthocyanidin
delphinidin in carbon tetrachloride (CCl4)-induced liver fibrosis in mice. Male Balb/C mice …
delphinidin in carbon tetrachloride (CCl4)-induced liver fibrosis in mice. Male Balb/C mice …
Naringenin attenuates CCl4‐induced hepatic inflammation by the activation of an Nrf2‐mediated pathway in rats
MA Esmaeili, M Alilou - Clinical and Experimental …, 2014 - Wiley Online Library
The possible protective effects of naringenin, a naturally occurring citrus flavonone, on
carbon tetrachloride (CCl4)‐induced liver injury in rats and the mechanism underlying its …
carbon tetrachloride (CCl4)‐induced liver injury in rats and the mechanism underlying its …
[HTML][HTML] Dihydrokaempferol attenuates CCl4-induced hepatic fibrosis by inhibiting PARP-1 to affect multiple downstream pathways and cytokines
H Huang, S Wei, X Wu, M Zhang, B Zhou… - Toxicology and Applied …, 2023 - Elsevier
The pathophysiological mechanism of hepatic fibrosis (HF) is related to the excessive
activation of the DNA repair enzyme poly ADP-ribose polymerase-1 (PARP-1). The drugs …
activation of the DNA repair enzyme poly ADP-ribose polymerase-1 (PARP-1). The drugs …
Protective effect and mechanism of action of mulberry marc anthocyanins on carbon tetrachloride-induced liver fibrosis in rats
Y Li, Z Yang, S Jia, K Yuan - Journal of Functional Foods, 2016 - Elsevier
Mulberry fruit is widely consumed either fresh or in processed food products such as juice,
mulberry jelly and jam. Conversely, mulberry marc, the solid component after juicing, is …
mulberry jelly and jam. Conversely, mulberry marc, the solid component after juicing, is …
Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation
N Dai, Y Zou, L Zhu, HF Wang, MG Dai - Journal of medicinal food, 2014 - liebertpub.com
Liver steatosis is characterized by lipid dysregulation and fat accumulation in the liver and
can lead to oxidative stress in liver. Since proanthocyanidins are present in plant-based …
can lead to oxidative stress in liver. Since proanthocyanidins are present in plant-based …
Protective effects of anthocyanins from purple sweet potato on acute carbon tetrachloride-induced oxidative hepatotoxicity fibrosis in mice
M Zhang, LJ Pan, ST Jiang, YW Mo - Food and Agricultural …, 2016 - Taylor & Francis
The present study was designed to evaluate the antioxidant activities of anthocyanins
obtained from purple sweet potato (PSPAs) and their protective effect on hepatic fibrosis …
obtained from purple sweet potato (PSPAs) and their protective effect on hepatic fibrosis …
Puerarin mediates hepatoprotection against CCl4-induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function
R Li, L Xu, T Liang, Y Li, S Zhang, X Duan - Food and chemical toxicology, 2013 - Elsevier
This study was designed to evaluate the potential effects of puerarin (PR), an effective
isoflavonoid compound purified from Pueraria lobata, in treating hepatic fibrosis (HF) rats …
isoflavonoid compound purified from Pueraria lobata, in treating hepatic fibrosis (HF) rats …